Manghnani, Purnima N;
Nelson, Arif Z;
Wong, Kelvin;
Lee, Yi Wei;
Khan, Saif A;
Doyle, Patrick S;
(2024)
From burst to controlled release: using hydrogel crosslinking chemistry to tune release of micro-crystalline active pharmaceutical ingredients.
RSC Pharmaceutics
10.1039/d4pm00186a.
(In press).
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Abstract
In this study, a nanoemulsion of a BCS class II drug, fenofibrate, was cross-linked via a Michael-type addition reaction to yield micro-crystalline Fen-embedded micro-hydrogels with tunable degradation.
| Type: | Article |
|---|---|
| Title: | From burst to controlled release: using hydrogel crosslinking chemistry to tune release of micro-crystalline active pharmaceutical ingredients |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/d4pm00186a |
| Publisher version: | http://dx.doi.org/10.1039/d4pm00186a |
| Language: | English |
| Additional information: | This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. See: http://creativecommons.org/licenses/by-nc/3.0/ |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10200554 |
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