Viñals Gonzalez, Xavier;
Akompey, Kassie;
Sen Gupta, Sioban;
Nicholls, Jacqueline;
(2024)
A matter of choice? – patient decision-making and support in non-euploid embryo transfers.
Human Fertility
, 27
(1)
, Article 2431118. 10.1080/14647273.2024.2431118.
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Abstract
Deciding whether to transfer a non-euploid embryo presents a challenge for both individuals and clinicians involved in assisted reproductive technologies (ART) with preimplantation genetic testing (PGT). The uncertainty surrounding clinical outcomes and long-term effects complicates this decision, and there is limited research on the factors that influence individuals’ experiences during this decision-making process. An online survey was utilized to gather data on elements influencing the decision-making process. The survey included both closed and open questions and targeted individuals worldwide who had undergone PGT during their fertility journey. A total of 135 responses were received, with complete data from 111 respondents analyzed. Three primary factors emerged as significant influences on respondents’ decision-making: the opportunity to discuss the implications of the transfer, the topics covered during consultations, and the country where the treatment was received. The study also identified three major themes related to the challenges faced by respondents: mismatched expectations, inadequate information provision, and an unsupportive decision-making process. These results highlight the critical need for appropriate support when deciding to transfer a non-euploid embryo. Respondents emphasized the importance of comprehensive discussions about the implications of PGT results. The study underscores the necessity for proactive clinic communication, patient-centred information, and increased support for patients considering non-euploid embryos.
| Type: | Article |
|---|---|
| Title: | A matter of choice? – patient decision-making and support in non-euploid embryo transfers |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/14647273.2024.2431118 |
| Publisher version: | http://dx.doi.org/10.1080/14647273.2024.2431118 |
| Language: | English |
| Additional information: | © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Non-euploid embryo; mosaic embryo; assisted reproductive technologies; preimplantation genetic testing; patient decisionmaking; clinical outcomes and patient support |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Reproductive Health |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10200583 |
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