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Repeatability and reproducibility of oxygen-enhanced MRI of the lung at 3 tesla: cross-center, cross-vendor evaluation

Kim, Mina; Needleman, Sarah; Naish, Josephine; Taylor, Yohn; Tibiletti, Marta; O’Connor, James; Parker, Geoff; (2023) Repeatability and reproducibility of oxygen-enhanced MRI of the lung at 3 tesla: cross-center, cross-vendor evaluation. Presented at: 2023 ISMRM & ISMRT Annual Meeting, Toronto, Canada. Green open access

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Abstract

A recently developed protocol with a dual echo RF-spoiled gradient echo acquisition enabled simultaneous measurement of dynamic OE signal change and the substantial ∆R2* effect at 3 tesla. To progress towards clinical translation, we evaluated repeatability and reproducibility across two sites, vendors and time points. Our results demonstrate good repeatability for the quantitative and semi-quantitative indices across time points, consistent signal behaviour and repeatable ∆R2* across two sites and vendors, suggesting potential utility in multi-centre clinical studies. However, echo time dependence should be considered when interpreting percentage signal enhancement.

Type: Conference item (Presentation)
Title: Repeatability and reproducibility of oxygen-enhanced MRI of the lung at 3 tesla: cross-center, cross-vendor evaluation
Event: 2023 ISMRM & ISMRT Annual Meeting
Location: Toronto, Canada
Dates: 3 Jun 2023 - 8 Jun 2023
Open access status: An open access version is available from UCL Discovery
DOI: 10.58530/2023/4812
Publisher version: http://dx.doi.org/10.58530/2023/4812
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10200595
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