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X-ray computed tomography

Withers, Philip J; Bouman, Charles; Carmignato, Simone; Cnudde, Veerle; Grimaldi, David; Hagen, Charlotte K; Maire, Eric; ... Stock, Stuart R; + view all (2021) X-ray computed tomography. Nature Reviews Methods Primers , 1 , Article 18. 10.1038/s43586-021-00015-4. Green open access

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Abstract

X-ray computed tomography (CT) can reveal the internal details of objects in three dimensions non-destructively. In this Primer, we outline the basic principles of CT and describe the ways in which a CT scan can be acquired using X-ray tubes and synchrotron sources, including the different possible contrast modes that can be exploited. We explain the process of computationally reconstructing three-dimensional (3D) images from 2D radiographs and how to segment the 3D images for subsequent visualization and quantification. Whereas CT is widely used in medical and heavy industrial contexts at relatively low resolutions, here we focus on the application of higher resolution X-ray CT across science and engineering. We consider the application of X-ray CT to study subjects across the materials, metrology and manufacturing, engineering, food, biological, geological and palaeontological sciences. We examine how CT can be used to follow the structural evolution of materials in three dimensions in real time or in a time-lapse manner, for example to follow materials manufacturing or the in-service behaviour and degradation of manufactured components. Finally, we consider the potential for radiation damage and common sources of imaging artefacts, discuss reproducibility issues and consider future advances and opportunities.

Type: Article
Title: X-ray computed tomography
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s43586-021-00015-4
Publisher version: https://doi.org/10.1038/s43586-021-00015-4
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10201520
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