Buckley, Vanessa;
Young, Allan H;
Smith, Patrick;
(2023)
Child and adolescent anxiety as a risk factor for bipolar disorder: A systematic review of longitudinal studies.
Bipolar Disorders
, 25
(4)
pp. 278-288.
10.1111/bdi.13322.
Preview |
Text
Buckley_Bipolar Disorders - 2023 - Buckley - Child and adolescent anxiety as a risk factor for bipolar disorder A systematic_1.pdf Download (460kB) | Preview |
Abstract
OBJECTIVES: Several studies have suggested that anxiety disorders in childhood and adolescence often precede the onset of bipolar disorder. We therefore systematically reviewed the relationship between child and adolescent anxiety and later bipolar disorder. METHODS: Online databases (Medline [for Ovid], EMBASE and PsychINFO) were searched for original, peer‐reviewed studies examining the relationship between child and adolescent anxiety and later bipolar disorder. Studies in both community samples and bipolar offspring samples were included. RESULTS: A total of 16 studies were included in the review. The results were broadly consistent and revealed that child and adolescent anxiety disorders are associated with later bipolar disorder in community samples. In bipolar offspring, child and adolescent anxiety disorders are a marker of increased risk and predict the onset of bipolar disorder and other major mood disorders. CONCLUSIONS: There is evidence that anxiety disorders in childhood and adolescence increase the risk of later bipolar disorder. Anxiety disorders may be a useful target for early intervention in those at high‐risk of bipolar disorder.
| Type: | Article |
|---|---|
| Title: | Child and adolescent anxiety as a risk factor for bipolar disorder: A systematic review of longitudinal studies |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/bdi.13322 |
| Publisher version: | https://doi.org/10.1111/bdi.13322 |
| Language: | English |
| Additional information: | © 2023 The Authors. Bipolar Disorders published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Adolescence, anxiety, bipolar disorder, childhood, risk factor |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10204251 |
Archive Staff Only
 |
View Item |
