Bonelli, SB;
Thompson, PJ;
Yogarajah, M;
Vollmar, C;
Powell, RH;
Symms, MR;
McEvoy, AW;
... Duncan, JS; + view all
(2012)
Imaging language networks before and after anterior temporal lobe resection: results of a longitudinal fMRI study.
Epilepsia
, 53
(4)
639 - 650.
10.1111/j.1528-1167.2012.03433.x.
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Abstract
Anterior temporal lobe resection (ATLR) controls seizures in up to 70% of patients with intractable temporal lobe epilepsy (TLE) but, in the language dominant hemisphere, may impair language function, particularly naming. Functional reorganization can occur within the ipsilateral and contralateral hemispheres. We investigated reorganization of language in left-hemisphere-dominant patients before and after ATLR; whether preoperative functional magnetic resonance imaging (fMRI) predicts postoperative naming decline; and efficiency of postoperative language networks.
| Type: | Article |
|---|---|
| Title: | Imaging language networks before and after anterior temporal lobe resection: results of a longitudinal fMRI study. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/j.1528-1167.2012.03433.x |
| Publisher version: | http://dx.doi.org/10.1111/j.1528-1167.2012.03433.x |
| Language: | English |
| Additional information: | Wiley Periodicals, Inc. © 2012 International League Against Epilepsy. Full text made available to UCL Discovery by kind permission of Wiley. |
| Keywords: | Adolescent, Adult, Anterior Temporal Lobectomy, Brain Mapping, Electroencephalography, Epilepsy, Temporal Lobe, Female, Frontal Lobe, Genetic Testing, Humans, Image Processing, Computer-Assisted, Language Disorders, Longitudinal Studies, Magnetic Resonance Imaging, Male, Middle Aged, Neural Pathways, Neuropsychological Tests, Oxygen, Sensitivity and Specificity, Treatment Outcome, Verbal Behavior, Young Adult |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1343984 |
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