CANCER RESEARCH TECHNOLOGY LIMITED, R. Brown, J. Plumb, G. W. Aherne, E. Mcdonald, K. Jones, S. Hilton
(2007)
Preparation of 2-[3H]-thiazol-2-ylidine-methylpyridine and related compounds and their use as antitumor agents.
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Abstract
The present invention pertains to certain 2-[3H-thiazol-2-ylidinemethyl]pyridine compounds and analogs thereof, which, inter alia, inhibit cell proliferation, treat cancer, etc., and more specifically to compounds of the following formula, wherein RA1, RA2, RA3, RA4, RB1, RB2, RNA, RNB, and X- are as defined herein. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative conditions such as cancer, etc.
| Type: | Patent |
|---|---|
| Title: | Preparation of 2-[3H]-thiazol-2-ylidine-methylpyridine and related compounds and their use as antitumor agents |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | http://patentscope.wipo.int/search/en/WO2007096618 |
| Language: | English |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1353075 |
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