NEIDLE, S;
TAYLOR, G;
COWLING, P;
(1979)
CRYSTAL AND MOLECULAR-STRUCTURE OF 8,2'-CYCLOADENOSINE TRIHYDRATE.
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE
, 35
(Part 3)
708 - 712.
10.1107/S0567740879004490.
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Abstract
8,2'-Cycloadenosine, C IoHi~NsO4.3H20, is a modified arabinosyladenosine nucleoside which has been cyclized at the C(8) and 0(2') atoms. THe trihydrate crystallizes in the orthorhombic space group P2~2~2~, with a = 8.680 (2), b = 5.991 (2), c = 27.203 (4) A, Z = 4. The structure was refined to R = 0.0672 for 1411 unique reflections, photographically recorded. The arabinofuranose ring has a flattened C(4')-endo-C(3')- exo pucker. The conformation about C(4')-C(5') is gauche-gauche, and that about the sugar-base bond is high anti. The crystal structure involves extensive base-base hydrogen bonding, N(1), N(6) and N(7) all being participants.
| Type: | Article |
|---|---|
| Title: | CRYSTAL AND MOLECULAR-STRUCTURE OF 8,2'-CYCLOADENOSINE TRIHYDRATE |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1107/S0567740879004490 |
| Publisher version: | http://scripts.iucr.org/cgi-bin/paper?S05677408790... |
| Language: | English |
| Additional information: | Copyright © International Union of Crystallography |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1367864 |
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