Gibb, DM;
Kizito, H;
Russell, EC;
Chidziva, E;
Zalwango, E;
Nalumenya, R;
Spyer, M;
... DART trial team, The; + view all
(2012)
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial.
PLoS Medicine
, 9
(5)
, Article e1001217. 10.1371/journal.pmed.1001217.
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Abstract
Few data have described long-term outcomes for infants born to HIV-infected African women taking antiretroviral therapy (ART) in pregnancy. This is particularly true for World Health Organization (WHO)-recommended tenofovir-containing first-line regimens, which are increasingly used and known to cause renal and bone toxicities; concerns have been raised about potential toxicity in babies due to in utero tenofovir exposure.
| Type: | Article |
|---|---|
| Title: | Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. |
| Location: | US |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pmed.1001217 |
| Publisher version: | http://dx.doi.org/10.1371/journal.pmed.1001217 |
| Language: | English |
| Additional information: | © 2012 Gibb et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3352861 |
| Keywords: | Abortion, Spontaneous, Adenine, Adult, Anti-HIV Agents, Body Height, Body Weight, Breast Feeding, Burns, Cause of Death, Child, Preschool, Congenital Abnormalities, Drug Combinations, Female, Follow-Up Studies, Fractures, Bone, Growth, HIV Infections, HIV Seropositivity, Humans, Infant, Infant Mortality, Infant, Newborn, Infectious Disease Transmission, Vertical, Lamivudine, Male, Measles, Organophosphonates, Pregnancy, Pregnancy Complications, Infectious, Pregnancy Outcome, Prevalence, Respiratory Tract Infections, Uganda, Zidovudine, Zimbabwe |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1373459 |
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