Lashley, T;
Hardy, J;
Isaacs, AM;
(2013)
RANTing about C9orf72.
Neuron
, 77
(4)
597 - 598.
10.1016/j.neuron.2013.02.009.
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Abstract
A noncoding repeat expansion in the C9orf72 gene is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. In this issue of Neuron, Ash et al. (2013) show that despite being noncoding the repeats are translated, leading to widespread neuronal aggregates of the translated proteins.
| Type: | Article |
|---|---|
| Title: | RANTing about C9orf72 |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.neuron.2013.02.009 |
| Publisher version: | http://dx.doi.org/10.1016/j.neuron.2013.02.009 |
| Language: | English |
| Additional information: | This article is available under an Elsevier user license http://www.elsevier.com/about/open-access/open-access-policies/oa-license-policy/elsevier-user-license Articles published under an Elsevier user license are protected by copyright and may be used for non-commercial purposes. Users may access, download, copy, translate, text mine and data mine the articles provided that users: Cite the article using an appropriate bibliographic citation (i.e. author(s), journal, article title, volume, issue, page numbers, DOI and the link to the definitive published version on ScienceDirect) Use the article for non- commercial purposes Maintain the integrity of the article Retain copyright notices and links to these terms and conditions so it is clear to other users what can and cannot be done with the article Ensure that, for any content in the article that is identified as belonging to a third party, any re-use complies with the copyright policies of that third party Any translations, for which a prior translation agreement with Elsevier has not been established, must prominently display the statement: "This is an unofficial translation of an article that appeared in an Elsevier publication. Elsevier has not endorsed this translation." |
| Keywords: | Amyotrophic Lateral Sclerosis, Cohort Studies, DNA-Binding Proteins, Frontotemporal Dementia, Genotype, Humans, Neurons, Proteins |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1388391 |
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