Callaghan, MF;
Helms, G;
Lutti, A;
Mohammadi, S;
Weiskopf, N;
(2015)
A general linear relaxometry model of R1 using imaging data.
Magn Reson Med
, 73
(3)
1309 - 1314.
10.1002/mrm.25210.
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Abstract
The longitudinal relaxation rate (R1 ) measured in vivo depends on the local microstructural properties of the tissue, such as macromolecular, iron, and water content. Here, we use whole brain multiparametric in vivo data and a general linear relaxometry model to describe the dependence of R1 on these components. We explore a) the validity of having a single fixed set of model coefficients for the whole brain and b) the stability of the model coefficients in a large cohort.
| Type: | Article |
|---|---|
| Title: | A general linear relaxometry model of R1 using imaging data |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/mrm.25210 |
| Publisher version: | http://dx.doi.org/10.1002/mrm.25210 |
| Language: | English |
| Additional information: | © 2014 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | 3T, MT, PD, PD*, R1, R2*, T1, T2*, longitudinal relaxation, magnetization transfer, quantitative, relaxometry, transverse relaxation, water content |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1426376 |
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