Masi, S;
D'Aiuto, F;
Martin-Ruiz, C;
Kahn, T;
Wong, A;
Ghosh, AK;
Whincup, P;
... NSHD scientific and data collection teams, .; + view all
(2014)
Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort.
Eur Heart J
, 35
(46)
3296 - 3303.
10.1093/eurheartj/ehu226.
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Abstract
Cross-sectional studies reported associations between short leucocyte telomere length (LTL) and measures of vascular and cardiac damage. However, the contribution of LTL dynamics to the age-related process of cardiovascular (CV) remodelling remains unknown. In this study, we explored whether the rate of LTL shortening can predict CV phenotypes over 10-year follow-up and the influence of established CV risk factors on this relationship.
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