Parker, S;
Gil, E;
Hewitt, P;
Ward, K;
Reyal, Y;
Wilson, S;
Manson, J;
(2014)
Case report: passive transfer of hepatitis B antibodies from intravenous immunoglobulin.
BMC Infectious Diseases
, 14
(1)
99 - 99.
10.1186/1471-2334-14-99.
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Abstract
Background: Prior to initiating immunosuppressive therapy in the treatment of autoimmune inflammatory conditions, it is a requirement to screen for certain viral serology, including hepatitis B (HBV). A positive result may indicate the need for antiviral therapy, or contraindicate immunosuppression all together. An accurate interpretation of serological markers is therefore imperative in order to treat patients appropriately. We present a case of passive anti-HBV antibody transfer following intravenous immunoglobulin (IVIg) infusion, in which misinterpretation of serology results almost led to inappropriate treatment with antiviral therapy and the withholding of immunosuppressive agents. This phenomenon has been previously reported, but awareness remains limited.
| Type: | Article |
|---|---|
| Title: | Case report: passive transfer of hepatitis B antibodies from intravenous immunoglobulin |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1471-2334-14-99 |
| Publisher version: | http://dx.doi.org/10.1186/1471-2334-14-99 |
| Language: | English |
| Additional information: | © 2014 Parker et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1449527 |
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