van Wijk, BC;
Jha, A;
Penny, W;
Litvak, V;
(2015)
Parametric estimation of cross-frequency coupling.
Journal of Neuroscience Methods
, 243
pp. 94-102.
10.1016/j.jneumeth.2015.01.032.
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Abstract
Growing experimental evidence suggests an important role for cross-frequency coupling in neural processing, in particular for phase-amplitude coupling (PAC). Although the details of methods to detect PAC may vary, a common procedure to estimate the significance level is the comparison of observed values to those of at least 100 surrogate time series. When scanning large parts of the frequency spectrum and multiple recording sites, this could amount to very large computation times.
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