Snoek, KG;
Reiss, IKM;
Greenough, A;
Capolupo, I;
Urlesberger, B;
Wessel, L;
Storme, L;
... Tibboel, D; + view all
(2016)
Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update.
Neonatology
, 110
(1)
pp. 66-74.
10.1159/000444210.
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Abstract
In 2010, the congenital diaphragmatic hernia (CDH) EURO Consortium published a standardized neonatal treatment protocol. Five years later, the number of participating centers has been raised from 13 to 22. In this article the relevant literature is updated, and consensus has been reached between the members of the CDH EURO Consortium. Key updated recommendations are: (1) planned delivery after a gestational age of 39 weeks in a high-volume tertiary center; (2) neuromuscular blocking agents to be avoided during initial treatment in the delivery room; (3) adapt treatment to reach a preductal saturation of between 80 and 95% and postductal saturation >70%; (4) target PaCO2 to be between 50 and 70 mm Hg; (5) conventional mechanical ventilation to be the optimal initial ventilation strategy, and (6) intravenous sildenafil to be considered in CDH patients with severe pulmonary hypertension. This article represents the current opinion of all consortium members in Europe for the optimal neonatal treatment of CDH.
| Type: | Article |
|---|---|
| Title: | Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1159/000444210 |
| Publisher version: | http://dx.doi.org/10.1159/000444210 |
| Language: | English |
| Additional information: | Copyright © 2016 The Author(s). Published by S. Karger AG, Basel. This article is licensed under the Creative Commons AttributionNonCommercial-NoDerivatives 4.0 International License (CC BY NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). See http://www.karger.com/Services/OpenAccessLicense. Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission. |
| Keywords: | Congenital diaphragmatic hernia; Standardized treatment; Consensus |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1492699 |
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