Witoonpanich, P;
Crutch, SJ;
Warren, JD;
Rossor, MN;
(2015)
The undiscovered syndrome: Macdonald Critchley's case of semantic dementia.
Neurocase
, 21
(4)
pp. 408-412.
10.1080/13554794.2014.910307.
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Abstract
Semantic dementia is a unique clinicopathological syndrome in the frontotemporal lobar degeneration spectrum. It is characterized by progressive and relatively selective impairment of semantic memory, associated with asymmetric antero-inferior temporal lobe atrophy. Although the syndrome became widely recognized only in the 1980s, descriptions of cases with typical features of semantic dementia have been on record for over a century. Here, we draw attention to a well documented historical case of a patient with features that would have fulfilled current consensus criteria for semantic dementia, as reconstructed from the notes made by her neurologist, Macdonald Critchley, in 1938. This case raises a number of issues concerning the nosology of the semantic dementia syndrome and the potential value of archived case material.
| Type: | Article |
|---|---|
| Title: | The undiscovered syndrome: Macdonald Critchley's case of semantic dementia |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/13554794.2014.910307 |
| Publisher version: | http://dx.doi.org/10.1080/13554794.2014.910307 |
| Language: | English |
| Additional information: | Copyright © 2014 The Author(s). Published by Taylor & Francis. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | semantic dementia, Macdonald Critchley, historical, nosology |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1496081 |
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