Swallow, DM;
Troelsen, JT;
(2016)
Escape from epigenetic silencing of lactase expression is triggered by a single-nucleotide change.
Nature: Structural & Molecular Biology
, 23
(6)
pp. 505-507.
10.1038/nsmb.3238.
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Abstract
The importance of subtle gene regulation and epigenetics in determining complex human traits is increasingly being recognized. However, bridging the gaps between environmental, epigenetic and genetic influences and unraveling causal relationships remain a big challenge. A study now reports an example of epigenetic changes influenced by genetic factors that are involved in the regulation of lactase gene expression.
| Type: | Article |
|---|---|
| Title: | Escape from epigenetic silencing of lactase expression is triggered by a single-nucleotide change |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/nsmb.3238 |
| Publisher version: | http://doi.org/10.1038/nsmb.3238 |
| Language: | English |
| Additional information: | Copyright © 2016 Nature America, Inc. All rights reserved. |
| Keywords: | DNA methylation, Genetics |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1499842 |
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