Thornton, JS;
(2016)
Technical challenges and safety of magnetic resonance imaging with in situ neuromodulation from spine to brain.
European Journal of Paediatric Neurology
, 21
(1)
pp. 232-241.
10.1016/j.ejpn.2016.06.001.
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Abstract
PURPOSE: This review summarises the need for MRI with in situ neuromodulation, the key safety challenges and how they may be mitigated, and surveys the current status of MRI safety for the main categories of neuro-stimulation device, including deep brain stimulation, vagus nerve stimulation, sacral neuromodulation, spinal cord stimulation systems, and cochlear implants. REVIEW SUMMARY: When neuro-stimulator systems are introduced into the MRI environment a number of hazards arise with potential for patient harm, in particular the risk of thermal injury due to MRI-induced heating. For many devices however, safe MRI conditions can be determined, and MRI safely performed, albeit with possible compromise in anatomical coverage, image quality or extended acquisition time. CONCLUSIONS: The increasing availability of devices conditional for 3 T MRI, whole-body transmit imaging, and imaging in the on-stimulation condition, will be of significant benefit to the growing population of patients benefitting from neuromodulation therapy, and open up new opportunities for functional imaging research.
Type: | Article |
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Title: | Technical challenges and safety of magnetic resonance imaging with in situ neuromodulation from spine to brain |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.ejpn.2016.06.001 |
Publisher version: | http://doi.org/10.1016/j.ejpn.2016.06.001 |
Language: | English |
Additional information: | © 2016 Published by Elsevier Ltd on behalf of European Paediatric Neurology Society. This manuscript version is made available under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at https://creativecommons.org/licenses/. Access may be initially restricted by the publisher. |
Keywords: | MR imaging, MRI, Neuromodulation, Neurostimulation, Safety |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1507551 |
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