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Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation

Futter, CE; Cutler, DF; (2016) Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation. Journal of Cell Biology , 214 (3) pp. 245-247. 10.1083/jcb.201607023. Green open access

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Abstract

Melanosome biogenesis requires successive waves of cargo delivery from endosomes to immature melanosomes, coupled with recycling of the trafficking machinery. Dennis et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605090) report differential roles for BLOC-1 and BLOC-3 complexes in delivery and recycling of melanosomal biogenetic components, supplying directionality to melanosome maturation.

Type: Article
Title: Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1083/jcb.201607023
Publisher version: http://doi.org/10.1083/jcb.201607023
Language: English
Additional information: © 2016 Futter and Cutler. This article is distributed under the terms of an Attribution– Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
Keywords: Science & Technology, Life Sciences & Biomedicine, Cell Biology, LYSOSOME-RELATED ORGANELLES, EXCHANGE FACTOR, CARGO DELIVERY, ENDOSOMES, VARP, BIOGENESIS, RAB38, VAMP7
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Lab for Molecular Cell Bio MRC-UCL
URI: https://discovery-pp.ucl.ac.uk/id/eprint/1511913
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