Piper, MDW;
Partridge, L;
(2016)
Protocols to Study Aging in Drosophila.
In:
Drosophila.
(pp. 291-302).
Springer: New York, NY, USA.
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Abstract
The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.
| Type: | Book chapter |
|---|---|
| Title: | Protocols to Study Aging in Drosophila |
| ISBN-13: | 978-1-4939-6369-0 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-1-4939-6371-3_18 |
| Publisher version: | https://doi.org/10.1007/978-1-4939-6371-3_18 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| Keywords: | Aging, Backcross, Diet, Drosophila melanogaster, Genetic interventions, Life span, Method, Pharmacological interventions, Aging, Animals, Animals, Genetically Modified, Biochemistry, Complex Mixtures, Crosses, Genetic, Diet, Drosophila melanogaster, Feeding Behavior, Female, Male, Phenotype, Sucrose, Yeasts, Zygote |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1522674 |
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