Makin, TR;
Bensmaia, SJ;
(2017)
Stability of Sensory Topographies in Adult Cortex.
Trends in Cognitive Sciences
, 21
(3)
pp. 195-204.
10.1016/j.tics.2017.01.002.
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Abstract
Textbooks teach us that the removal of sensory input to sensory cortex, for example, following arm amputation, results in massive reorganisation in the adult brain. In this opinion article, we critically examine evidence for functional reorganisation of sensory cortical representations, focusing on the sequelae of arm amputation on somatosensory topographies. Based on literature from human and non-human primates, we conclude that the cortical representation of the limb remains remarkably stable despite the loss of its main peripheral input. Furthermore, the purportedly massive reorganisation results primarily from the formation or potentiation of new pathways in subcortical structures and does not produce novel functional sensory representations. We discuss the implications of the stability of sensory representations on the development of upper-limb neuroprostheses.
| Type: | Article |
|---|---|
| Title: | Stability of Sensory Topographies in Adult Cortex |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.tics.2017.01.002 |
| Publisher version: | http://dx.doi.org/10.1016/j.tics.2017.01.002 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | MASSIVE CORTICAL REORGANIZATION, LARGE-SCALE REORGANIZATION, HUMAN CEREBRAL-CORTEX, SPINAL-CORD INJURIES, PRIMARY MOTOR CORTEX, PHANTOM-LIMB PAIN, SOMATOSENSORY CORTEX, MACAQUE MONKEYS, PERCEPTUAL PLASTICITY, VISUAL DEPRIVATION |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Institute of Cognitive Neuroscience |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1547826 |
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