Salcher, M;
Mcguire, A;
Muthurangu, V;
Kelm, M;
Kuehne, T;
Naci, H;
(2017)
Avoidable costs of stenting for aortic coarctation in the United Kingdom: an economic model.
BMC Health Services Research
, 17
, Article 258. 10.1186/s12913-017-2215-2.
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Abstract
BACKGROUND: Undesirable outcomes in health care are associated with patient harm and substantial excess costs. Coarctation of the aorta (CoA), one of the most common congenital heart diseases, can be repaired with stenting but requires monitoring and subsequent interventions to detect and treat disease recurrence and aortic wall injuries. Avoidable costs associated with stenting in patients with CoA are unknown. METHODS: We developed an economic model to calculate potentially avoidable costs in stenting treatment of CoA in the United Kingdom over 5 years. We calculated baseline costs for the intervention and potentially avoidable complications and follow-up interventions and compared these to the costs in hypothetical scenarios with improved treatment effectiveness and complication rates. RESULTS: Baseline costs were £16 688 ($25 182) per patient. Avoidable costs ranged from £137 ($207) per patient in a scenario assuming a 10% reduction in aortic wall injuries and reinterventions at follow-up, to £1627 ($2455) in a Best-case scenario with 100% treatment success and no complications. Overall costs in the Best-case scenario were 90.2% of overall costs at Baseline. Reintervention rate at follow-up was identified as most influential lever for overall costs. Probabilistic sensitivity analysis showed a considerable degree of uncertainty for avoidable costs with widely overlapping 95% confidence intervals. CONCLUSIONS: Significant improvements in the treatment effectiveness and reductions in complication rates are required to realize discernible cost savings. Up to 10% of total baseline costs could be avoided in the best-case scenario. This highlights the need to pursue patient-specific treatment approaches which promise optimal outcomes.
| Type: | Article |
|---|---|
| Title: | Avoidable costs of stenting for aortic coarctation in the United Kingdom: an economic model |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/s12913-017-2215-2 |
| Publisher version: | http://doi.org/10.1186/s12913-017-2215-2 |
| Language: | English |
| Additional information: | © The Author(s). 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Health Care Sciences & Services, Coarctation of the aorta, Stents, Heart defects, Congenital, Avoidable costs, Cost savings, CONGENITAL HEART-DISEASE, TERM-FOLLOW-UP, CHEATHAM-PLATINUM STENTS, CARDIAC-CATHETERIZATION, HEALTH-CARE, INTERMEDIATE, IMPLANTATION, QUALITY, REPAIR, CONSORTIUM |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1555360 |
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