Maughan Jones, CJ;
Munro, PRT;
(2017)
Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone.
Journal of Biomedical Optics
, 22
(9)
, Article 095004. 10.1117/1.JBO.22.9.095004.
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Abstract
Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. Solutions to these problems were developed and an improved method, incorporating these solutions, is presented. The improved method offers excellent reliability and reproducibility for creating phantoms with uniform scattering coefficient. We also present evidence of decreased sphere aggregation.
| Type: | Article |
|---|---|
| Title: | Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/1.JBO.22.9.095004 |
| Publisher version: | http://doi.org/10.1117/1.JBO.22.9.095004 |
| Language: | English |
| Additional information: | © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.JBO.22.9.095004] |
| Keywords: | Optical scattering; spectrophotometry; phantoms; Mie theory |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1574377 |
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