Mathews, MA;
Camp, AJ;
Murray, AJ;
(2017)
Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits.
Frontiers in Physiology
, 8
, Article 552. 10.3389/fphys.2017.00552.
Preview |
Text (Published article)
fphys-08-00552.pdf - Published Version Download (1MB) | Preview |
Preview |
Text (Corrigendum dated 30 May 2018)
Corrigendum%3A Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits.pdf Download (905kB) | Preview |
Abstract
Efferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The function of this efferent vestibular system (EVS) in vestibular and motor coordination though, has proven difficult to determine, and remains under debate. We consider current literature that implicate corollary discharge from the spinal cord through the efferent vestibular nucleus (EVN), and hint at a potential role in overall vestibular plasticity and compensation. Hypotheses range from differentiating between passive and active movements at the level of vestibular afferents, to EVS activation under specific behavioral and environmental contexts such as arousal, predation, and locomotion. In this review, we summarize current knowledge of EVS circuitry, its effects on vestibular hair cell and primary afferent activity, and discuss its potential functional roles.
| Type: | Article |
|---|---|
| Title: | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fphys.2017.00552 |
| Publisher version: | http://doi.org/10.3389/fphys.2017.00552 |
| Language: | English |
| Additional information: | Corrigendum issued 30 May 2018. - Copyright © 2017 Mathews, Camp and Murray. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | efferent vestibular system, efferent vestibular nucleus, EVS, EVN, corollary discharge, VOR, vestibular, vestibular plasticity |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > The Sainsbury Wellcome Centre |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1575490 |
Archive Staff Only
 |
View Item |
