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Number of items: 317.

A

Abdul-Kadir, Rezan; Gomez, Keith; (2022) Reproductive health and hemostatic issues in women and girls with congenital factor VII deficiency: A systematic review. Journal of Thrombosis and Haemostasis , 20 (12) pp. 2758-2772. 10.1111/jth.15872. Green open access
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Agbuduwe, Charles; Iqbal, Gulnaz; Cairns, David A; Menzies, Tom; Dunn, Janet; Gregory, Walter Martin; Kaiser, Martin F; ... Basu, Supratik; + view all (2022) Clinical Characteristics and Outcomes of IgD Myeloma: Experience across UK National Trials. Blood Advances 10.1182/bloodadvances.2022007608. (In press). Green open access
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Agerbæk, M; Bang-Christensen, SR; Yang, MH; Clausen, TM; Pereira, MA; Sharma, S; Ditlev, SB; ... Salanti, A; + view all (2022) Author Correction to: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner (Nature Communications, (2018), 9, 1, (3279), 10.1038/s41467-018-05793-2). Nature Communications , 13 (1) , Article 3285. 10.1038/s41467-022-29351-z. Green open access
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Aggarwal, D; Page, AJ; Schaefer, U; Savva, GM; Myers, R; Volz, E; Ellaby, N; ... Harrison, EM; + view all (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications , 13 , Article 1012. 10.1038/s41467-022-28371-z. Green open access
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Ahrenfeldt, Johanne; Christensen, Ditte S; Sokac, Mateo; Kisistok, Judit; McGranahan, Nicholas; Birkbak, Nicolai J; (2022) Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer. Cancers , 14 (23) , Article 5817. 10.3390/cancers14235817. Green open access
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Amodeo, Valeria; Davies, Timothy; Martinez-Segura, Amalia; Clements, Melanie; Ragdale, Holly Simpson; Bailey, Andrew; Silva Dos Santos, Mariana; ... Parrinello, Simona; + view all (2022) Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells. bioRxiv: Cold Spring Harbor, NY, USA. Green open access
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Ariëns, RA; Hunt, BJ; Agbani, EO; Ahnström, J; Ahrends, R; Alikhan, R; Assinger, A; ... Zhou, J; + view all (2022) Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress. Research and Practice in Thrombosis and Haemostasis , 6 (5) , Article e12747. 10.1002/rth2.12747. Green open access
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Ascierto, Paolo A; Agarwala, Sanjiv S; Blank, Christian; Caraco, Corrado; Carvajal, Richard D; Ernstoff, Marc S; Ferrone, Soldano; ... Thurin, Magdalena; + view all (2022) Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy). Journal of Translational Medicine , 20 , Article 391. 10.1186/s12967-022-03592-4. Green open access
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Asghar, US; Kanani, R; Roylance, R; Mittnacht, S; (2022) Systematic Review of Molecular Biomarkers Predictive of Resistance to CDK4/6 Inhibition in Metastatic Breast Cancer. JCO Precision Oncology , 6 pp. 1-13. 10.1200/po.21.00002. Green open access
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Ashby, C; Boyle, EM; Bauer, MA; Mikulasova, A; Wardell, CP; Williams, L; Siegel, A; ... Morgan, GJ; + view all (2022) Structural variants shape the genomic landscape and clinical outcome of multiple myeloma. Blood Cancer Journal , 12 (5) , Article 85. 10.1038/s41408-022-00673-x. Green open access
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Asher, Samir; Kazantzi, Aikaterini; Dekaj, Fatjon; Steventon, Luke; Khatun, Aisha; Ainley, Louise; McMillan, Annabel; ... Popat, Rakesh; + view all (2022) Under-representation of ethnic minorities in early phase clinical trials for multiple myeloma. Haematologica , 107 (12) pp. 2961-2965. 10.3324/haematol.2022.281322. Green open access
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Ashford, F; Best, A; Dunn, SJ; Ahmed, Z; Siddiqui, H; Melville, J; Wilkinson, S; ... Jamrozy, D; + view all (2022) SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time. Journal of Clinical Microbiology , 60 (4) , Article e02408-21. 10.1128/jcm.02408-21. Green open access
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Atsamnia, Djamel; Hanini, Salah; Oukrif, Dahmane; Benachour, Karine; Benkortbi, Othmane; Hamadache, Mabrouk; (2022) Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats. Kemija u Industriji , 71 (3-4) pp. 141-149. 10.15255/kui.2021.035. Green open access
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B

Bahl, Amit; Wilson, William; Ball, Jessica; Renninson, Emily; Dubey, Sidharth; Bravo, Alicia; Foulstone, Emily; ... Churn, Mark; + view all (2022) Concept: A randomised multicentre trial of first line chemotherapy comparing three weekly cabazitaxel versus weekly paclitaxel in HER2 negative metastatic breast cancer. The Breast , 66 pp. 69-76. 10.1016/j.breast.2022.09.005. Green open access
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Bakhai, Ameet; McCauley, Leah; Stones, Liba; Khalil, Saria; Mehta, Jay; Price, Nicola; Krishnamurthy, Vinodh; ... Hughes, Derralynn; + view all (2022) Shining a light on an additional clinical burden: work-related digital communication survey study – COVID-19 impact on NHS staff wellbeing. Humanities and Social Sciences Communications , 9 , Article 414. 10.1057/s41599-022-01427-7. Green open access
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Barber, Paul R; Mustapha, Rami; Flores-Borja, Fabian; Alfano, Giovanna; Ng, Kenrick; Weitsman, Gregory; Dolcetti, Luigi; ... Ng, Tony; + view all (2022) Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development. eLife , 11 , Article e73288. 10.7554/eLife.73288. Green open access
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Barmpoutis, P; Waddingham, W; Ross, C; Hamzeh, K; Alexander, DC; Jansen, M; (2022) Gland segmentation in gastric histology images: detection of intestinal metaplasia. In: 2022 30th European Signal Processing Conference (EUSIPCO). (pp. pp. 1338-1342). IEEE: Belgrade, Serbia. Green open access
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Barmpoutis, Panagiotis; Yuan, Jing; Waddingham, William; Ross, Christopher; Hamzeh, Kayhanian; Stathaki, Tania; Alexander, Daniel C; (2022) Multi-scale Deformable Transformer for the Classification of Gastric Glands: The IMGL Dataset. In: Ali, S and VanDerSommen, F and Papiez, BW and VanEijnatten, M and Jin, Y and Kolenbrander, I, (eds.) MICCAI Workshop on Cancer Prevention through Early Detection CaPTion 2022: Cancer Prevention Through Early Detection. (pp. pp. 24-33). Springer, Cham Green open access
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Beaton, Laura; Tregidgo, Henry Fj; Znati, Sami A; Forsyth, Sharon; Counsell, Nicholas; Clarkson, Matthew J; Bandula, Steven; ... Sharma, Ricky A; + view all (2022) Phase 0 study of vandetanib-eluting radiopaque embolics as a pre-operative embolization treatment in patients with resectable liver malignancies. Journal of Vascular and Interventional Radiology , 33 (9) 1034-1044.e29. 10.1016/j.jvir.2022.04.033. Green open access
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Beck, Michael; Ramaswami, Uma; Hernberg-Stahl, Elizabeth; Hughes, Derralynn A; Kampmann, Christoph; Mehta, Atul B; Nicholls, Kathleen; ... Giugliani, Roberto; + view all (2022) Twenty years of the Fabry Outcome Survey (FOS): insights, achievements, and lessons learned from a global patient registry. Orphanet Journal of Rare Diseases , 17 , Article 238. 10.1186/s13023-022-02392-9. Green open access
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Beird, H; Bielack, Stefan; Flanagan, Adrienne; Gill, B; Heymann, Dominique; Janeway, Katherine; Livingston, JA; ... Gorlick, Richard; + view all (2022) Osteosarcoma. Nature Reviews Disease Primers , 8 , Article 77. 10.1038/s41572-022-00409-y. Green open access
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Bennett, Clare; (2022) Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages. Cell Reports , 39 (7) , Article 110819. 10.1016/j.celrep.2022.110819. Green open access
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Bergstrom, Erik N; Luebeck, Jens; Petljak, Mia; Khandekar, Azhar; Barnes, Mark; Zhang, Tongwu; Steele, Christopher D; ... Alexandrov, Ludmil B; + view all (2022) Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA. Nature 10.1038/s41586-022-04398-6. (In press). Green open access
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Berndt, Sonja I; Vijai, Joseph; Benavente, Yolanda; Camp, Nicola J; Nieters, Alexandra; Wang, Zhaoming; Smedby, Karin E; ... Rothman, Nathaniel; + view all (2022) Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes. Leukemia , 36 (12) pp. 2835-2844. 10.1038/s41375-022-01711-0. Green open access
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Best, Jonathan G; Arram, Liz; Ahmed, Norin; Balogun, Maryam; Bennett, Kate; Bordea, Ekaterina; Campos, Marta G; ... OPTIMAS investigators, .; + view all (2022) Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial. International Journal of Stroke , 17 (5) pp. 583-589. 10.1177/17474930211057722. Green open access
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Bolik, J; Krause, F; Stevanovic, M; Gandraß, M; Thomsen, I; Schacht, S-S; Rieser, E; ... Schmidt-Arras, D; + view all (2022) Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis. J Exp Med , 219 (1) , Article e20201039. 10.1084/jem.20201039. Green open access
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Bonsor, Daniel A; Alexander, Patrick; Snead, Kelly; Hartig, Nicole; Drew, Matthew; Messing, Simon; Finci, Lorenzo I; ... Simanshu, Dhirendra K; + view all (2022) Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome. Nature Structural and Molecular Biology , 29 (10) pp. 966-977. 10.1038/s41594-022-00841-4. Green open access
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Bortolomeazzi, Michele; Montorsi, Lucia; Temelkovski, Damjan; Keddar, Mohamed Reda; Acha-Sagredo, Amelia; Pitcher, Michael J; Basso, Gianluca; ... Ciccarelli, Francesca D; + view all (2022) A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution. Nature Communications , 13 , Article 781. 10.1038/s41467-022-28470-x. Green open access
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Boumelha, Jesse; de Carné Trécesson, Sophie; Law, Emily K; Romero-Clavijo, Pablo; Coelho, Matthew; Ng, Kevin; Mugarza, Edurne; ... Downward, Julian; + view all (2022) An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations. Cancer Research , 82 (19) pp. 3435-3448. 10.1158/0008-5472.CAN-22-0325. Green open access
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Bowes, Amy; Tarabichi, Maxime; Pillay, Nischalan; Van Loo, Peter; (2022) Leveraging single cell sequencing to unravel intra-tumour heterogeneity and tumour evolution in human cancers. Journal of Pathology , 257 (4) pp. 466-478. 10.1002/path.5914. Green open access
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Breeze, CE; Beck, S; Berndt, SI; Franceschini, N; (2022) The missing diversity in human epigenomic studies. Nature Genetics , 54 pp. 737-739. 10.1038/s41588-022-01081-4. Green open access
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Breeze, CE; Haugen, E; Reynolds, A; Teschendorff, A; van Dongen, J; Lan, Q; Rothman, N; ... Berndt, SI; + view all (2022) Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome Biololgy , 23 (1) , Article 13. 10.1186/s13059-021-02560-3. Green open access
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Breeze, Charles E; Wong, Jason YY; Beck, Stephan; Berndt, Sonja I; Franceschini, Nora; (2022) Diversity in EWAS: current state, challenges, and solutions. Genome Medicine , 14 , Article 71. 10.1186/s13073-022-01065-3. Green open access
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Brennan, B; Kirton, L; Marec-Bérard, P; Gaspar, N; Laurence, V; Martín-Broto, J; Sastre, A; ... Wheatley, K; + view all (2022) Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial. The Lancet , 400 (10362) pp. 1513-1521. 10.1016/S0140-6736(22)01790-1. Green open access
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Bridgewater, John; Fletcher, Peter; Palmer, Daniel H; Malik, Hassan Z; Prasad, Raj; Mirza, Darius; Anthony, Alan; ... BILCAP study group, .; + view all (2022) Long-Term Outcomes and Exploratory Analyses of the Randomized Phase III BILCAP Study. Journal of Clinical Oncology , 40 (18) pp. 2048-2057. 10.1200/JCO.21.02568. Green open access
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Bridgewater, John; Jiao, Xiaolong; Parimi, Mounika; Flach, Clare; Stratford, Jeran; Kamburov, Atanas; Schmitz, Arndt A; ... Bazhenova, Lyudmila; + view all (2022) Prognosis and oncogenomic profiling of patients with tropomyosin receptor kinase fusion cancer in the 100,000 genomes project. Cancer Treatment and Research Communications , 33 , Article 100623. 10.1016/j.ctarc.2022.100623. Green open access
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Brimble, MA; Cheng, PH; Winston, SM; Reeves, IL; Souquette, A; Spence, Y; Zhou, J; ... Davidoff, AM; + view all (2022) Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps. Molecular Therapy - Methods and Clinical Development , 24 pp. 280-291. 10.1016/j.omtm.2022.01.008. (In press). Green open access
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Brooks, Lucy J; Clements, Melanie P; Burden, Jemima J; Kocher, Daniela; Richards, Luca; Devesa, Sara Castro; Zakka, Leila; ... Parrinello, Simona; + view all (2022) Author Correction: The white matter is a pro-differentiative niche for glioblastoma. Nature Communications , 13 (1) , Article 2163. 10.1038/s41467-022-29916-y. Green open access
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Brooks, Lucy J; Simpson Ragdale, Holly; Hill, Ciaran Scott; Clements, Melanie; Parrinello, Simona; (2022) Injury programs shape glioblastoma. Trends in Neurosciences 10.1016/j.tins.2022.08.006. (In press). Green open access
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Brown, Sarah R; Hinsley, Samantha; Hall, Emma; Hurt, Chris; Baird, Richard D; Forster, Martin; Scarsbrook, Andrew F; (2022) A Road Map for Designing Phase I Clinical Trials of Radiotherapy–Novel Agent Combinations. Clinical Cancer Research , 28 (17) pp. 3639-3651. 10.1158/1078-0432.CCR-21-4087. Green open access
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Budde, Axel; Baust, Katja; Weinhold, Leonie; Bernstein, Mark; Bielack, Stefan; Dhooge, Catharina; Hjorth, Lars; ... Schmid, Matthias; + view all (2022) Erratum to 'Linking EORTC QLQ-C-30 and PedsQL/PEDQOL physical functioning scores in patients with osteosarcoma' [Eur J Cancer 170 (2022) 209-235]. European Journal of Cancer , 177 pp. 208-209. 10.1016/j.ejca.2022.06.053. Green open access
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Bustoros, Mark; Anand, Shankara; Sklavenitis-Pistofidis, Romanos; Redd, Robert; Boyle, Eileen M; Zhitomirsky, Benny; Dunford, Andrew J; ... Ghobrial, Irene M; + view all (2022) Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes. Nature Communications , 13 , Article 3449. 10.1038/s41467-022-30694-w. Green open access
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C

Cabeza-Segura, M; Gambardella, V; Gimeno-Valiente, F; Carbonell-Asins, JA; Alarcón-Molero, L; González-Vilanova, A; Zuñiga-Trejos, S; ... Fleitas, T; + view all (2022) Integrative immune transcriptomic classification improves patient selection for precision immunotherapy in advanced gastro-oesophageal adenocarcinoma. British Journal of Cancer , 127 (12) pp. 2198-2206. 10.1038/s41416-022-02005-z. Green open access
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Camilleri, Marquita; Bekris, Georgios; Sidhu, Govundeep; Buck, Caroline; Elsden, Esma; McCourt, Orla; Horder, Jackie; ... Fisher, Abigail; + view all (2022) The impact of COVID-19 on autologous stem cell transplantation in multiple myeloma: A single-centre, qualitative evaluation study. Supportive Care in Cancer 10.1007/s00520-022-07173-5. (In press). Green open access
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Campbell, Rachel; Costa, Daniel SJ; Stockler, Martin R; Lee, Yeh Chen; Ledermann, Jonathan A; Berton, Dominique; Sehouli, Jalid; ... GCIG Symptom Benefit Group; + view all (2022) Measure of Ovarian Symptoms and Treatment concerns (MOST) indexes and their associations with health-related quality of life in recurrent ovarian cancer. Gynecologic Oncology , 166 (2) pp. 254-262. 10.1016/j.ygyno.2022.05.024. Green open access
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Cardenas, Andres; Ecker, Simone; Fadadu, Raj P; Huen, Karen; Orozco, Allan; McEwen, Lisa M; Engelbrecht, Hannah-Ruth; ... Rehkopf, David H; + view all (2022) Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults. Scientific Reports , 12 , Article 4277. 10.1038/s41598-022-08160-w. Green open access
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Casali, PG; Blay, JY; Abecassis, N; Bajpai, J; Bauer, S; Biagini, R; Bielack, S; ... Stacchiotti, S; + view all (2022) Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology , 33 (1) pp. 20-33. 10.1016/j.annonc.2021.09.005. Green open access
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Chakravarthy, Ankur; Reddin, Ian; Henderson, Stephen; Dong, Cindy; Kirkwood, Nerissa; Jeyakumar, Maxmilan; Rodriguez, Daniela Rothschild; ... Fenton, Tim R; + view all (2022) Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance. Nature Communications , 13 , Article 5818. 10.1038/s41467-022-33544-x. Green open access
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Chan, WY; Counsell, N; de Tute, R; De-Silva, D; Phillips, EH; Cavenagh, J; Adedayo, T; ... Yong, KL; + view all (2022) Outcomes of relapse in patients with deferred autologous stem cell transplant after achieving at least very good partial response following bortezomib, adriamycin, dexamethasone chemotherapy for newly diagnosed multiple myeloma in the phase II PADIMAC trial. British Journal of Haematology , 196 (4) e33-e37. 10.1111/bjh.17903. Green open access
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Chan, WY; Zhu, C; Sanchez, E; Gupta, R; Fielding, AK; Khwaja, A; Payne, EM; (2022) Antibody responses to SARS-CoV-2 vaccination in patients with acute myeloid leukaemia and high risk MDS on active anti-cancer therapies. British Journal of Haematology , 198 (3) pp. 478-481. 10.1111/bjh.18248. Green open access
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Chandy, Edward T. J.; (2022) Quantitative Analysis of Radiation-Associated Parenchymal Lung Change. Doctoral thesis (M.D(Res)), UCL (University College London). Green open access
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Charalambous, Xenia; (2022) Tumour-Priming of Human Natural Killer Cells and the Impact of Tumour Microenvironment in Ovarian Cancer. Doctoral thesis (Ph.D), UCL (University College London. Green open access
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Chen, Kezhong; Yang, Airong; Carbone, David P; Kanu, Nnennaya; Liu, Ke; Wang, Ruiru; Nie, Yuntao; ... Wang, Jun; + view all (2022) Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers. Cell Reports , 40 (2) , Article 111047. 10.1016/j.celrep.2022.111047. Green open access
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Chen, Yu-Guang; (2022) Investigating the role of the linear ubiquitin chain assembly complex in lymphotoxin beta receptor signalling and obesity-derived hepatitis. Doctoral thesis (Ph.D), UCL (University College London).

Cheok, Kathleen PL; Kirkwood, Amy A; Menne, Tobias; Tholouli, Eleni; Chaganti, Sridhar; Mathew, Amrith; Uttenthal, Ben; ... Roddie, Claire; + view all (2022) Severe presentations and high mortality from SARS-CoV-2 in patients undergoing chimeric antigen receptor (CAR-T) therapy: a UK NCCP analysis. Leukemia & Lymphoma , 63 (8) pp. 1980-1984. 10.1080/10428194.2022.2057487. Green open access
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Chervova, Olga; Chernysheva, Elizabeth; Panteleeva, Kseniia; Widayati, Tyas Arum; Hrbkova, Natalie; Schneider, Jadesada; Maximov, Vladimir; ... Beck, Stephan; + view all (2022) Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort. Biology , 12 (1) , Article 68. 10.3390/biology12010068. Green open access
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Chowdary, P; Nathwani, A; (2022) Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B: The authors reply. New England Journal of Medicine , 387 (14) pp. 1336-1337. 10.1056/NEJMc2210918. Green open access
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Chowdary, P; Shapiro, S; Makris, M; Evans, G; Boyce, S; Talks, K; Dolan, G; ... Nathwani, A; + view all (2022) Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B. The New England Journal of Medicine , 387 (3) pp. 237-247. 10.1056/NEJMoa2119913. Green open access
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Christensen, Ditte S; Ahrenfeldt, Johanne; Sokac, Mateo; Kisistok, Judit; Thomsen, Martin K; Maretty, Lasse; McGranahan, Nicholas; (2022) Treatment Represents a Key Driver of Metastatic Cancer Evolution. Cancer Research , 82 (16) pp. 2918-2927. 10.1158/0008-5472.CAN-22-0562. Green open access
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Cooke, EA; Smith, NAS; Thomas, SA; Ruston, C; Hothi, S; Hughes, D; (2022) An integrated discrete event simulation and particle swarm optimisation model for optimising efficiency of cancer diagnosis pathways. Healthcare Analytics , 2 , Article 100082. 10.1016/j.health.2022.100082. Green open access
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Cortellini, Alessio; Aguilar-Company, Juan; Salazar, Ramon; Bower, Mark; Sita-Lumsden, Ailsa; Plaja, Andrea; Lee, Alvin JX; ... Pinato, David J; + view all (2022) Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer. British Journal of Cancer 10.1038/s41416-022-01952-x. (In press). Green open access
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Cortellini, Alessio; Gennari, Alessandra; Pommeret, Fanny; Patel, Grisma; Newsom-Davis, Thomas; Bertuzzi, Alexia; Viladot, Margarita; ... OnCovid study group, .; + view all (2022) COVID-19 Sequelae and the Host Pro-Inflammatory Response: An Analysis From the OnCovid Registry. JNCI: Journal of the National Cancer Institute , 114 (7) pp. 979-987. 10.1093/jnci/djac057. Green open access
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Cortellini, Alessio; Salazar, Ramon; Gennari, Alessandra; Aguilar-Company, Juan; Bower, Mark; Bertuzzi, Alexia; Brunet, Joan; ... Pinato, David J; + view all (2022) Persistence of long-term COVID-19 sequelae in patients with cancer: an analysis from the OnCovid registry. European Journal of Cancer , 170 pp. 10-16. 10.1016/j.ejca.2022.03.019. Green open access
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Cottone, Lucia; Ligammari, Lorena; Lee, Hang-Mao; Knowles, Helen J; Henderson, Stephen; Bianco, Sara; Davies, Christopher; ... Flanagan, Adrienne M; + view all (2022) Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone. Cell Death & Differentiation , 29 pp. 2459-2471. 10.1038/s41418-022-01031-x. Green open access
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Cross, William; Lyskjær, Iben; Lesluyes, Tom; Hargreaves, Steven; Strobl, Anna-Christina; Davies, Christopher; Waise, Sara; ... Flanagan, Adrienne M; + view all (2022) A genetic model for central chondrosarcoma evolution correlates with patient outcome. Genome Medicine , 14 (1) , Article 99. 10.1186/s13073-022-01084-0. Green open access
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D

Dale, Katie L; Armond, Jonathan W; Hynds, Robert E; Vladimirou, Elina; (2022) Modest increase of KIF11 exposes fragilities in the mitotic spindle causing chromosomal instability. Journal of Cell Science , 135 (17) , Article jcs.260031. 10.1242/jcs.260031. Green open access
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Dardis, A; Michelakakis, H; Rozenfeld, P; Fumic, K; Wagner, J; Pavan, E; Fuller, M; ... Aerts, J; + view all (2022) Patient centered guidelines for the laboratory diagnosis of Gaucher disease type 1. Orphanet Journal of Rare Diseases , 17 , Article 442. 10.1186/s13023-022-02573-6. Green open access
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Davies, Faith E; Pawlyn, Charlotte; Usmani, Saad Z; San-Miguel, Jesus F; Einsele, Hermann; Boyle, Eileen M; Corre, Jill; ... Morgan, Gareth J; + view all (2022) Perspectives on the Risk-Stratified Treatment of Multiple Myeloma. Blood Cancer Discovery , 3 (4) pp. 273-284. 10.1158/2643-3230.BCD-21-0205. Green open access
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Day, James W; Fox, Thomas A; Gupta, Rajeev; Khwaja, Asim; Wilson, Andrew J; Kottaridis, Panagiotis D; (2022) Gilteritinib monotherapy as a transplant bridging option for high risk FLT3-mutated AML with t(6;9)(p23;q34.1);DEK-NUP214 in morphological but not cytogenetic or molecular remission following standard induction chemotherapy. Leukemia Research Reports , 17 , Article 100291. 10.1016/j.lrr.2022.100291. Green open access
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Dinneen, E; Allen, C; Strange, T; Heffernan-Ho, D; Banjeglav, J; Lindsay, J; Mulligan, JP; ... Punwani, S; + view all (2022) Negative mpMRI Rules Out Extra-Prostatic Extension in Prostate Cancer before Robot-Assisted Radical Prostatectomy. Diagnostics , 12 (5) , Article 1057. 10.3390/diagnostics12051057. Green open access
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Dixon, Peter H; Levine, Adam P; Cebola, Inês; Chan, Melanie MY; Amin, Aliya S; Aich, Anshul; Mozere, Monika; ... Williamson, Catherine; + view all (2022) GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements. Nature Communications , 13 , Article 4840. 10.1038/s41467-022-29931-z. Green open access
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Djebbari, F; Rampotas, A; Vallance, G; Panitsas, F; Basker, N; Sangha, G; Salhan, B; ... Ramasamy, K; + view all (2022) Efficacy of Isatuximab with Pomalidomide and Dexamethasone in Relapsed Myeloma: Results of a UK-Wide Real-World Dataset. HemaSphere , 6 (6) , Article e738. 10.1097/HS9.0000000000000738. Green open access
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Doki, Yuichiro; Ajani, Jaffer A; Kato, Ken; Xu, Jianming; Wyrwicz, Lucjan; Motoyama, Satoru; Ogata, Takashi; ... CheckMate 648 Trial Investigators; + view all (2022) Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma. New England Journal of Medicine , 386 (5) pp. 449-462. 10.1056/NEJMoa2111380. Green open access
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Dong, Lijun; Han, Haote; Huang, Xionggao; Ma, Gaoen; Fang, Dong; Qi, Hui; Han, Zhuo; ... Lei, Hetian; + view all (2022) Idelalisib inhibits experimental proliferative vitroretinopathy. Laboratory Investigation , 102 (12) pp. 1296-1303. 10.1038/s41374-022-00822-7. Green open access
file

Donnellan, C; Cohen, H; Werring, DJ; (2022) Cognitive dysfunction and associated neuroimaging biomarkers in antiphospholipid syndrome: a systematic review. Rheumatology , 61 (1) pp. 24-41. 10.1093/rheumatology/keab452. Green open access
file

Dupras, Charles; Knoppers, Terese; Palmour, Nicole; Beauchamp, Elisabeth; Liosi, Stamatina; Siebert, Reiner; Berner, Alison May; ... Joly, Yann; + view all (2022) Researcher perspectives on ethics considerations in epigenetics: an international survey. Clinical Epigenetics , 14 (1) , Article 110. 10.1186/s13148-022-01322-7. Green open access
file

E

Eales, O; Page, AJ; De Oliveira Martins, L; Wang, H; Bodinier, B; Haw, D; Jonnerby, J; ... Elliott, P; + view all (2022) SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. BMC Infectious Diseases , 22 , Article 647. 10.1186/s12879-022-07628-4. Green open access
file

Edeline, Julien; Meyer, Tim; Blanc, Jean-Frédéric; Raoul, Jean-Luc; (2022) New Challenges Facing Systemic Therapies of Advanced HCC in the Era of Different First-Line Immunotherapy-Based Combinations. Cancers , 14 (23) , Article 5868. 10.3390/cancers14235868. Green open access
file

Efthymiou, M; Lane, PJ; Isenberg, D; Cohen, H; Mackie, IJ; (2022) Comparison of acquired activated protein C resistance, using the CAT and ST-genesia® analysers and three thrombin generation methods, in APS and SLE patients. Journal of Clinical Medicine , 11 (1) , Article 69. 10.3390/jcm11010069. Green open access
file

El-Khoueiry, Anthony B; Meyer, Tim; Cheng, Ann-Lii; Rimassa, Lorenza; Sen, Suvajit; Milwee, Steven; Kelley, Robin Kate; (2022) Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child-Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial. BMC Cancer , 22 , Article 377. 10.1186/s12885-022-09453-z. Green open access
file

Elstein, D; Belmatoug, N; Deegan, P; Göker-Alpan, Ö; Hughes, DA; Schwartz, IVD; Weinreb, N; ... Zimran, A; + view all (2022) Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials. Orphanet Journal of Rare Diseases , 17 , Article 9. 10.1186/s13023-021-02163-y. Green open access
file

Engelbrecht, Hannah-Ruth; Merrill, Sarah M; Gladish, Nicole; MacIsaac, Julie L; Lin, David TS; Ecker, Simone; Chrysohoou, Christina A; ... Rehkopf, David H; + view all (2022) Sex differences in epigenetic age in Mediterranean high longevity regions. Frontiers in Aging , 3 , Article 1007098. 10.3389/fragi.2022.1007098. Green open access
file

Eschweiler, Simon; Ramírez-Suástegui, Ciro; Li, Yingcong; King, Emma; Chudley, Lindsey; Thomas, Jaya; Wood, Oliver; ... Ottensmeier, Christian H; + view all (2022) Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. Nature 10.1038/s41586-022-04685-2. (In press). Green open access
file

Evans, JA; Carlotti, E; Lin, M-L; Hackett, RJ; Haughey, MJ; Passman, AM; Dunn, L; ... McDonald, SA; + view all (2022) Clonal Transitions and Phenotypic Evolution in Barrett's Esophagus. Gastroenterology , 162 (4) 1197-1209.e13. 10.1053/j.gastro.2021.12.271. Green open access
file

F

Farmakis, Dimitrios; Porter, John; Taher, Ali; Cappellini, Maria Domenica; Angastiniotis, Michael; Eleftheriou, Androulla; (2022) 2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia. HemaSphere , 6 (8) , Article e732. 10.1097/HS9.0000000000000732. Green open access
file

Fernandes, Liane P; Enriquez-Gasca, Rocio; Gould, Poppy A; Holt, James H; Conde, Lucia; Ecco, Gabriela; Herrero, Javier; ... Rowe, Helen M; + view all (2022) A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819. Science Advances , 8 (43) , Article eabp8085. 10.1126/sciadv.abp8085. Green open access
file

Ferrada, Marcela A; Savic, Sinisa; Ospina Cardona, Daniela; Collins, Jason Charles; Alessi, Hugh; Gutierrez-Rodrigues, Fernanda; Uthaya Kumar, Dinesh Babu; ... Beck, David B; + view all (2022) Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis. Blood , 140 (13) pp. 1496-1506. 10.1182/blood.2022016985. Green open access
file

Fiaccadori, Valeria; (2022) Development of a CD30-directed CAR-T cell for the treatment of relapsed/refractory classical Hodgkin Lymphoma. Doctoral thesis (Ph.D), UCL (University College London).

Flynn, Michael J; Ledermann, Jonathan A; (2022) Ovarian cancer recurrence: is the definition of platinum resistance modified by PARPi and other intervening treatments? The evolving landscape in the management of platinum-resistant ovarian cancer. Cancer Drug Resistance , 5 (2) pp. 424-435. 10.20517/cdr.2022.13. Green open access
file

Frauenfelder, C; Hall, A; Walsh, B; Ross, A; Broughton, E; Hynds, RE; Nandi, R; ... Butler, CR; + view all (2022) Use of Simulation to Visualize Healthcare Worker Exposure to Aerosol in the Operating Room. Simulation in Healthcare , 17 (1) pp. 66-67. 10.1097/SIH.0000000000000581. Green open access
file

Freemantle, Nick; Mollon, Patrick; Meyer, Tim; Cheng, Ann-Lii; El-Khoueiry, Anthony B; Kelley, Robin K; Baron, Ari D; ... Abou-Alfa, Ghassan K; + view all (2022) Quality of life assessment of cabozantinib in patients with advanced hepatocellular carcinoma in the CELESTIAL trial. European Journal of Cancer , 168 pp. 91-98. 10.1016/j.ejca.2022.03.021. Green open access
file

Frenel, JS; Kim, JW; Aryal, N; Asher, R; Berton, D; Vidal, L; Pautier, P; ... Pujade-Lauraine, E; + view all (2022) Efficacy of subsequent chemotherapy for patients with BRCA1/2-mutated recurrent epithelial ovarian cancer progressing on olaparib versus placebo maintenance: post-hoc analyses of the SOLO2/ENGOT Ov-21 trial. Annals of Oncology , 33 (10) pp. 1021-1028. 10.1016/j.annonc.2022.06.011. Green open access
file

Frizziero, M; Kilgour, E; Simpson, KL; Rothwell, DG; Moore, DA; Frese, KK; Galvin, M; ... Dive, C; + view all (2022) Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma. Clinical Cancer Research , 28 (10) pp. 1999-2019. 10.1158/1078-0432.CCR-21-3058. Green open access
file

G

Ganguli, Sushila; (2022) The Effects of Oncogenic Ras on Epithelial Cell Division. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Garcia Diaz, Claudia; (2022) Novel de novo Glioblastoma mouse models reveal differences in the biology of the tumour bulk and invasive margin. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Gaspar, Pedro; Farinha, Filipa; Sayar, Zara; Efthymiou, Maria; Cohen, Hannah; Isenberg, David A; (2022) A one-point increase in the Damage Index for Antiphospholipid Syndrome (DIAPS) predicts mortality in thrombotic antiphospholipid syndrome. Clinical and Experimental Rheumatology 10.55563/clinexprheumatol/0gs167. (In press). Green open access
file

Gatenbee, CD; Baker, AM; Schenck, RO; Strobl, M; West, J; Neves, MP; Hasan, SY; ... Anderson, ARA; + view all (2022) Immunosuppressive niche engineering at the onset of human colorectal cancer. Nature Communications , 13 , Article 1798. 10.1038/s41467-022-29027-8. Green open access
file

Gazinska, Patrycja; Milton, Charlotte; Iacovacci, Jacopo; Ward, Joseph; Buus, Richard; Alaguthurai, Thanussuyah; Graham, Rosalind; ... Irshad, Sheeba; + view all (2022) Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers. Clinical Cancer Research pp. 4494-4508. 10.1158/1078-0432.CCR-22-0543. Green open access
file

Geron, Ifat; Savino, Angela Maria; Fishman, Hila; Tal, Noa; Brown, John; Turati, Virginia A; James, Chela; ... Izraeli, Shai; + view all (2022) An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia. Nature Communications , 13 , Article 659. 10.1038/s41467-022-28218-7. Green open access
file

Ghorani, Ehsan; (2022) Intratumour CD4 T cell differentiation skewing and loss of immune fitness in non-small cell lung cancer. Doctoral thesis (Ph.D), UCL (University College London).

Gilks, C Blake; Selinger, Christina I; Davidson, Ben; Köbel, Martin; Ledermann, Jonathan A; Lim, Diana; Malpica, Anais; ... McCluggage, W Glenn; + view all (2022) Data Set for the Reporting of Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma: Recommendations From the International Collaboration on Cancer Reporting (ICCR). International Journal of Gynecological Pathology , 41 (6) S119-S142. 10.1097/PGP.0000000000000908. Green open access
filefilefilefilefilefilefile

Gomez, K; (2022) Advances in the diagnosis of heritable platelet disorders. Blood Reviews , 56 , Article 100972. 10.1016/j.blre.2022.100972. Green open access
file

Gomez, V; Galazi, M; Weitsman, G; Monypenny, J; Al-Salemee, F; Barber, P; Ng, K; ... Ng, T; + view all (2022) HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models. Molecular Cancer Therapeutics , 21 (4) pp. 667-676. 10.1158/1535-7163.MCT-21-0320. Green open access
file

Gooding, Sarah; Ansari-Pour, Naser; Kazeroun, Mohammad H; Karagoz, Kubra; Polonskaia, Ann; Angulo Salazar, Mirian; Fitzsimons, Evelyn; ... Thakurta, Anjan; + view all (2022) Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma. Blood , 140 (16) pp. 1816-1821. 10.1182/blood.2022015909. Green open access
file

Green, HM; Counsell, N; Ward, A; McCormack, M; (2022) Neoadjuvant Chemotherapy in Locally Advanced Cervical Carcinoma – a Role in Patients with Para-aortic Lymph Node Involvement? A 10-year Institutional Experience. Clinical Oncology , 34 (7) e281-e290. 10.1016/j.clon.2021.12.005. Green open access
file

Grey, William; Rio-Machin, Ana; Casado, Pedro; Grönroos, Eva; Ali, Sara; Miettinen, Juho J; Bewicke-Copley, Findlay; ... Bonnet, Dominique; + view all (2022) CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia. Science Translational Medicine , 14 (650) , Article eabn3248. 10.1126/scitranslmed.abn3248. Green open access
file

Grist, Emily; (2022) Biomarker Development for Advanced Prostate Cancer. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

H

Hackshaw, Allan; Clarke, Christina A; Hartman, Anne-Renee; (2022) New genomic technologies for multi-cancer early detection: Rethinking the scope of cancer screening. Cancer Cell 10.1016/j.ccell.2022.01.012. (In press). Green open access
file

Hagos, Yeman B; Akarca, Ayse U; Ramsay, Alan; Rossi, Riccardo L; Pomplun, Sabine; Ngai, Victoria; Moioli, Alessia; ... Marafioti, Teresa; + view all (2022) High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma. Hematological Oncology 10.1002/hon.3003. (In press). Green open access
file

Hames-Fathi, S; Nottley, SWG; Pillay, N; (2022) Unravelling undifferentiated soft tissue sarcomas: insights from genomics. Histopathology , 80 (1) pp. 109-121. 10.1111/his.14446. Green open access
file

Harrasser, Micaela; Gohil, Satyen Harish; Lau, Hiu; Della Peruta, Marco; Muczynski, Vincent; Patel, Dominic; Miranda, Elena; ... Nathwani, Amit Chunilal; + view all (2022) Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC. Breast Cancer Research , 24 (1) , Article 39. 10.1186/s13058-022-01531-1. Green open access
file

Hatcher, J; Gil, E; Storey, N; Brown, JR; Hartley, JC; Breuer, J; Lucchini, G; ... Dunn, H; + view all (2022) Reactivation/relapse of SARS-CoV-2 in a child following haematopoietic stem cell transplantation, confirmed by whole genome sequencing, following apparent viral clearance. Journal of Infection 10.1016/j.jinf.2022.05.043. (In press). Green open access
file

Hatipoglu, Emine; (2022) Deciphering the Immune Landscape in Renal Cell Carcinoma and in Anti-PD-1 Therapy. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Heide, Timon; Househam, Jacob; Cresswell, George D; Spiteri, Inmaculada; Lynn, Claire; Mossner, Maximilian; Kimberley, Chris; ... Sottoriva, Andrea; + view all (2022) The co-evolution of the genome and epigenome in colorectal cancer. Nature 10.1038/s41586-022-05202-1. (In press). Green open access
file

Helfen, A; Rieß, J; Fehler, O; Stölting, M; An, Z; Kocman, V; Schnepel, A; ... Eisenblätter, M; + view all (2022) In vivo imaging of microenvironmental and anti-PD-L1-mediated dynamics in cancer using S100A8/S100A9 as an imaging biomarker. Neoplasia , 28 , Article 100792. 10.1016/j.neo.2022.100792. Green open access
file

Hernandez, Diana; Danby, Robert David; Querol, Sergio; (2022) Editorial: Umbilical cord blood and tissue in novel therapies and haematopoiesis research. Frontiers in Cell and Developmental Biology , 10 , Article 979306. 10.3389/fcell.2022.979306. Green open access
file

Hertweck, Arnulf; Vila de Mucha, Maria; Barber, Paul R; Dagil, Robert; Porter, Hayley; Ramos, Andres; Lord, Graham M; (2022) The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes. Nucleic Acids Research , Article gkac258. 10.1093/nar/gkac258. (In press). Green open access
file

Holm, Jeppe Sejerø; Funt, Samuel A; Borch, Annie; Munk, Kamilla Kjærgaard; Bjerregaard, Anne-Mette; Reading, James L; Maher, Colleen; ... Hadrup, Sine Reker; + view all (2022) Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma. Nature Communications , 13 , Article 1935. 10.1038/s41467-022-29342-0. Green open access
file

Holohan, Sean David; (2022) Dissecting the Role of Trisomy 21 in Childhood Acute Lymphoblastic Leukaemia. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Horgan, D; Borisch, B; Cattaneo, I; Caulfield, M; Chiti, A; Chomienne, C; Cole, A; ... von Meyenn, M; + view all (2022) Factors Affecting Citizen Trust and Public Engagement Relating to the Generation and Use of Real-World Evidence in Healthcare. International Journal of Environmental Research and Public Health , 19 (3) , Article 1674. 10.3390/ijerph19031674. Green open access
file

Hoskin, Peter J; Hopkins, Kirsten; Misra, Vivek; Holt, Tanya; McMenemin, Rhona; McKinna, Fiona; Madhavan, Krishnaswamy; ... Lopes, Andre; + view all (2022) Prognostic factors for survival and ambulatory status at 8 weeks with metastatic spinal cord compression in the SCORAD randomised trial. Radiotherapy and Oncology , 173 pp. 77-83. 10.1016/j.radonc.2022.05.017. Green open access
file

Hostettler, Isabel Charlotte; Seiffge, David; Wong, Andrew; Ambler, Gareth; Wilson, Duncan; Shakeshaft, Clare; Banerjee, Gargi; ... Werring, David; + view all (2022) APOE and Cerebral Small Vessel Disease Markers in Patients With Intracerebral Hemorrhage. Neurology , 99 (12) e1290-e1298. 10.1212/WNL.0000000000200851. Green open access
file

Hough, R; Lopes, A; Patrick, P; Russell, N; Raj, K; Tholouli, E; Snowden, JA; ... Marks, D; + view all (2022) Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation. Blood Advances , 6 (7) pp. 2414-2426. 10.1182/bloodadvances.2021005106. Green open access
file

Househam, Jacob; Heide, Timon; Cresswell, George D; Spiteri, Inmaculada; Kimberley, Chris; Zapata, Luis; Lynn, Claire; ... Graham, Trevor A; + view all (2022) Phenotypic plasticity and genetic control in colorectal cancer evolution. Nature 10.1038/s41586-022-05311-x. Green open access
file

Howard, Sasha R; Freeston, Sarah; Harrison, Barney; Izatt, Louise; Natu, Sonali; Newbold, Kate; Pomplun, Sabine; ... Gaze, Mark N; + view all (2022) Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline. Endocrine-Related Cancer , 29 (11) G1-G33. 10.1530/ERC-22-0035. Green open access
file

Howell, Rowan; Clarke, Matthew A; Reuschl, Ann-Kathrin; Chen, Tianyi; Abbott-Imboden, Sean; Singer, Mervyn; Lowe, David M; ... Fisher, Jasmin; + view all (2022) Executable network of SARS-CoV-2-host interaction predicts drug combination treatments. npj Digital Medicine , 5 (1) , Article 18. 10.1038/s41746-022-00561-5. Green open access
file

HSIB; (2022) Clinical decision making: diagnosis and treatment of pulmonary embolism in emergency departments. Healthcare Safety Investigation Branch

Huerne, Katherine; Palmour, Nicole; Wu, Angela Ruohao; Beck, Stephan; Berner, Alison; Siebert, Reiner; Joly, Yann; (2022) Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing. The CRISPR Journal 10.1089/crispr.2021.0094. Green open access
file

Hughes, Derralynn A; Aguiar, Patrício; Lidove, Olivier; Nicholls, Kathleen; Nowak, Albina; Thomas, Mark; Torra, Roser; ... Feriozzi, Sandro; + view all (2022) Do clinical guidelines facilitate or impede drivers of treatment in Fabry disease? Orphanet Journal of Rare Diseases , 17 (1) , Article 42. 10.1186/s13023-022-02181-4. Green open access
file

Hughes, Derralynn A; Bichet, Daniel G; Giugliani, Roberto; Hopkin, Robert J; Krusinska, Eva; Nicholls, Kathleen; Olivotto, Iacopo; ... Wilcox, William R; + view all (2022) Long-term multisystemic efficacy of migalastat on Fabry-associated clinical events, including renal, cardiac and cerebrovascular outcomes. Journal of Medical Genetics 10.1136/jmg-2022-108669. (In press). Green open access
file

Hughes, Derralynn A; Deegan, Patrick; Giraldo, Pilar; Goker-Alpan, Ozlem; Lau, Heather; Lukina, Elena; Revel-Vilk, Shoshana; ... Zimran, Ari; + view all (2022) Switching between Enzyme Replacement Therapies and Substrate Reduction Therapies in Patients with Gaucher Disease: Data from the Gaucher Outcome Survey (GOS). Journal of Clinical Medicine , 11 (17) , Article 5158. 10.3390/jcm11175158. Green open access
file

Hung, King L; Luebeck, Jens; Dehkordi, Siavash R; Colón, Caterina I; Li, Rui; Wong, Ivy Tsz-Lo; Coruh, Ceyda; ... Chang, Howard Y; + view all (2022) Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature Genetics 10.1038/s41588-022-01190-0. (In press). Green open access
file

Hynds, Robert E; (2022) Exploiting the potential of lung stem cells to develop pro-regenerative therapies. Biology Open , 11 (10) , Article bio059423. 10.1242/bio.059423. Green open access
file

I

Ikonomou, Laertis; Magnusson, Mattias; Dries, Ruben; Herzog, Erica L; Hynds, Robert; Borok, Zea; Park, Jin-Ah; ... Ryan, Amy L; + view all (2022) Stem cells, cell therapies, and bioengineering in lung biology and disease 2021. American Journal of Physiology: Lung Cellular and Molecular Physiology , 323 (3) L342-L354. 10.1152/ajplung.00113.2022. Green open access
file

Ingley, KM; Maleddu, A; Le Grange, F; Gerrand, C; Bleyer, A; Yasmin, E; Whelan, J; (2022) Current approaches to management of bone sarcoma in adolescent and young adult patients. Pediatric Blood & Cancer , 69 (2) , Article e29442. 10.1002/pbc.29442. Green open access
file

Islam, SMA; Díaz-Gay, M; Wu, Y; Barnes, M; Vangara, R; Bergstrom, EN; He, Y; ... Alexandrov, LB; + view all (2022) Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor. Cell Genomics , 2 (11) , Article 100179. 10.1016/j.xgen.2022.100179. Green open access
file

J

Jain, B; Ng, K; Santos, PMG; Taparra, K; Muralidhar, V; Mahal, BA; Vapiwala, N; ... Dee, EC; + view all (2022) Prostate Cancer Disparities in Risk Group at Presentation and Access to Treatment for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study With Disaggregated Ethnic Groups. JCO Oncology Practice , 18 (1) e204-e218. 10.1200/OP.21.00412. Green open access
file

Jamal-Hanjani, Mariam; (2022) Combining a national research autopsy programme with computational approaches to study cancer evolution and metastasis: an interview with Mariam Jamal-Hanjani. Communications Biology , 5 , Article 629. 10.1038/s42003-022-03550-2. Green open access
file

Jamshidi, A; Liu, MC; Klein, EA; Venn, O; Hubbell, E; Beausang, JF; Gross, S; ... Swanton, C; + view all (2022) Evaluation of cell-free DNA approaches for multi-cancer early detection. Cancer Cell , 40 (12) pp. 1537-1549. 10.1016/j.ccell.2022.10.022. Green open access
file

Jha, Ram; (2022) Development of a protein-protein displacement platform using an anti-minocycline single domain antibody and a dedicated displaceable peptide for the generation of an OFF-switch CAR T cell. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Jurj, A; Qian, D; Calin, GA; Litchfield, K; (2022) At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets. Annals of Oncology , 33 (12) pp. 1214-1216. 10.1016/j.annonc.2022.10.507. Green open access
file

Jurmeister, Philipp; Glöß, Stefanie; Roller, Renée; Leitheiser, Maximilian; Schmid, Simone; Mochmann, Liliana H; Payá Capilla, Emma; ... Capper, David; + view all (2022) DNA methylation-based classification of sinonasal tumors. Nature Communications , 13 (1) , Article 7148. 10.1038/s41467-022-34815-3. Green open access
file

K

Kaufmann, Tom L; Petkovic, Marina; Watkins, Thomas BK; Colliver, Emma C; Laskina, Sofya; Thapa, Nisha; Minussi, Darlan C; ... Schwarz, Roland F; + view all (2022) MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution. Genome Biology volume , 23 , Article 241. 10.1186/s13059-022-02794-9. Green open access
file

Kelly, SM; Effeney, R; Gaze, MN; Bernier-Chastagner, V; Blondeel, A; Clementel, E; Corning, C; ... Mandeville, HC; + view all (2022) QUARTET: A SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer. European Journal of Cancer , 172 pp. 209-220. 10.1016/j.ejca.2022.05.037. Green open access
file

Khwaja, Jahanzaib; Bomsztyk, Joshua; Mahmood, Shameem; Wisniowski, Brendan; Shah, Raakhee; Tailor, Anish; Yong, Kwee; ... Wechalekar, Ashutosh D; + view all (2022) High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis. Blood Cancer Journal , 12 (9) , Article 128. 10.1038/s41408-022-00717-2. Green open access
file

Kindler, Hedy L; Hammel, Pascal; Reni, Michele; Van Cutsem, Eric; Macarulla, Teresa; Hall, Michael J; Park, Joon Oh; ... Golan, Talia; + view all (2022) Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer. Journal of Clinical Oncology , 40 (34) pp. 3929-3939. 10.1200/JCO.21.01604. Green open access
file

Kleijn, Istvan T; Martínez-Segura, Amalia; Bertaux, François; Saint, Malika; Kramer, Holger; Shahrezaei, Vahid; Marguerat, Samuel; (2022) Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast. Life Science Alliance , 5 (5) , Article e202101223. 10.26508/lsa.202101223. Green open access
file

Klemm, Cinzia; Howell, Rowan SM; Thorpe, Peter H; (2022) ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens. BMC Bioinformatics , 23 (1) , Article 60. 10.1186/s12859-022-04586-1. Green open access
file

Kos, K; Aslam, MA; van de Ven, R; Wellenstein, MD; Pieters, W; van Weverwijk, A; Duits, DEM; ... de Visser, KE; + view all (2022) Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche. Cell Reports , 38 (9) , Article 110447. 10.1016/j.celrep.2022.110447. Green open access
file

Kuhnl, Andrea; Roddie, Claire; Kirkwood, Amy A; Tholouli, Eleni; Menne, Tobias; Patel, Amit; Besley, Caroline; ... McMillan, Andrew; + view all (2022) A national service for delivering CD19 CAR-Tin large B-cell lymphoma – The UK real-world experience. British Journal of Haematology , 198 (3) pp. 492-502. 10.1111/bjh.18209. Green open access
file

Kumar, Shankar; Parry, Thomas; Mallett, Sue; Bhatnagar, Gauraang; Plumb, Andrew; Walsh, Shaun; Scott, Nigel; ... Taylor, Stuart; + view all (2022) Diagnostic performance of magnetic resonance enterography disease activity indices compared with a histological reference standard for adult terminal ileal Crohn's disease: experience from the METRIC trial. Journal of Crohn's and Colitis 10.1093/ecco-jcc/jjac062. (In press). Green open access
file

L

Lalani, Zubair; Chu, Gillian; Hsu, Silas; Kagawa, Shaw; Xiang, Michael; Zaccaria, Simone; El-Kebir, Mohammed; (2022) CNAViz: An interactive webtool for user-guided segmentation of tumor DNA sequencing data. PLoS Computational Biology , 18 (10) , Article e1010614. 10.1371/journal.pcbi.1010614. (In press). Green open access
file

Lally, P; Miller, N; Roberts, A; Beeken, RJ; Greenfield, DM; Potts, HWW; Counsell, N; ... Fisher, A; + view all (2022) An app with brief behavioural support to promote physical activity after a cancer diagnosis (APPROACH): study protocol for a pilot randomised controlled trial. Pilot and Feasibility Studies , 8 (1) , Article 74. 10.1186/s40814-022-01028-w. Green open access
file

Land, Joanne; Hackett, Julia; Sidhu, Govundeep; Heinrich, Malgorzata; McCourt, Orla; Yong, Kwee L; Fisher, Abi; (2022) Myeloma patients' experiences of a supervised physical activity programme: a qualitative study. Support Care Cancer , 30 pp. 6273-6286. 10.1007/s00520-022-07062-x. Green open access
file

Lange, Joshua T; Rose, John C; Chen, Celine Y; Pichugin, Yuriy; Xie, Liangqi; Tang, Jun; Hung, King L; ... Mischel, Paul S; + view all (2022) The evolutionary dynamics of extrachromosomal DNA in human cancers. Nature Genetics 10.1038/s41588-022-01177-x. (In press). Green open access
file

Lauder, Sarah N; Smart, Kathryn; Bart, Valentina MT; Pires, Ana; Scott, Jake; Milutinovic, Stefan; Godkin, Andrew; ... Gallimore, Awen; + view all (2022) Treg-driven tumour control by PI3Kδ inhibition limits myeloid-derived suppressor cell expansion. British Journal of Cancer 10.1038/s41416-022-01917-0. (In press). Green open access
file

Le Tourneau, Christophe; Perret, Camille; Hackshaw, Allan; Blay, Jean-Yves; Nabholz, Christoph; Geissler, Jan; Do, Thy; ... Dienstmann, Rodrigo; + view all (2022) An Approach to Solving the Complex Clinicogenomic Data Landscape in Precision Oncology: Learnings From the Design of WAYFIND-R, a Global Precision Oncology Registry. JCO Precision Oncology , 6 (6) , Article e2200019. 10.1200/PO.22.00019. Green open access
file

Lechner, M; Liu, J; Counsell, N; Gillespie, D; Chandrasekharan, D; Ta, NH; Jumani, K; ... Lund, VJ; + view all (2022) The COVANOS trial – insight into post-COVID olfactory dysfunction and the role of smell training. Rhinology , 60 (3) pp. 188-199. 10.4193/Rhin21.470.

Lechner, M; Liu, J; Counsell, N; Gillespie, D; Chandrasekharan, D; Ta, NH; Jumani, K; ... Lund, VJ; + view all (2022) The burden of olfactory dysfunction during the COVID-19 pandemic in the United Kingdom. Rhinology 10.4193/Rhin22.232.

Lechner, M; Takahashi, Y; Turri-Zanoni, M; Liu, J; Counsell, N; Hermsen, M; Kaur, RP; ... Hanna, EY; + view all (2022) Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma. European Journal of Cancer , 162 pp. 221-236. 10.1016/j.ejca.2021.09.046. Green open access
file

Ledermann, JA; (2022) Testing for homologous recombination deficiency – does it provide new insights for the use of veliparib? Gynecologic Oncology , 164 (2) pp. 243-244. 10.1016/j.ygyno.2022.01.018. Green open access
file

Lee, DDH; Cardinale, D; Saman, Y; Hirst, RA; Wilson, N; Corden, V; Rutman, A; ... O'Callaghan, C; + view all (2022) COVID-19: Extensive epithelial damage and ciliary dyskinesia in hospitalised patients. Rhinology 10.4193/Rhin21.233. (In press).

Lee, Lennard YW; Ionescu, Maria C; Starkey, Thomas; Little, Martin; Tilby, Michael; Tripathy, Arvind R; Mckenzie, Hayley S; ... Johnson, Prof Peter; + view all (2022) COVID-19: Third dose booster vaccine effectiveness against breakthrough coronavirus infection, hospitalisations and death in patients with cancer: A population-based study. European Journal of Cancer 10.1016/j.ejca.2022.06.038. (In press). Green open access
file

Lee, Lennard YW; Starkey, Thomas; Ionescu, Maria C; Little, Martin; Tilby, Michael; Tripathy, Arvind R; Mckenzie, Hayley S; ... Robinson, Kate; + view all (2022) Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study. The Lancet Oncology , 23 (6) pp. 748-757. 10.1016/s1470-2045(22)00202-9. Green open access
file

Lee, Yeh Chen; King, Madeleine T; O'Connell, Rachel L; Lanceley, Anne; Joly, Florence; Hilpert, Felix; Davis, Alison; ... GCIG Symptom Benefit Group, .; + view all (2022) Symptom burden and quality of life with chemotherapy for recurrent ovarian cancer: the Gynecologic Cancer InterGroup-Symptom Benefit Study. International Journal of Gynecologic Cancer 10.1136/ijgc-2021-003142. (In press). Green open access
file

Leng, H; Zhang, H; Li, L; Zhang, S; Wang, Y; Chavda, SJ; Galas-Filipowicz, D; ... Horwood, NJ; + view all (2022) Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease. Nature Communications , 13 (1) , Article 7868. 10.1038/s41467-022-35358-3. Green open access
file

Li, Xiang; Huang, Chun-Hao; Sánchez-Rivera, Francisco J; Kennedy, Margaret C; Tschaharganeh, Darjus F; Morris, John P; Montinaro, Antonella; ... Lowe, Scott W; + view all (2022) A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proceedings of the National Academy of Sciences , 119 (17) , Article e2110557119. 10.1073/pnas.2110557119. Green open access
file

Lin, S; Araujo, C; Hall, A; Kumar, R; Phillips, A; Hassan, M; Engelmann, C; ... Jalan, R; + view all (2022) Prognostic Role of Liver Biopsy in Patients With Severe Indeterminate Acute Hepatitis. Clinical Gastroenterology and Hepatology , 20 (5) 1130-1141.e7. 10.1016/j.cgh.2021.08.008. Green open access
filefile

Lin, S; Hall, A; Kumar, R; Quaglia, A; Jalan, R; (2022) Validation of the SURFASA score to define steroid responsiveness in patients with acute autoimmune hepatitis. Journal of Hepatology , 76 (2) pp. 485-487. 10.1016/j.jhep.2021.08.013. Green open access
file

Liu, ZJ; Deschmann, E; Ramsey, HE; Feldman, HA; Psaila, B; Cooper, N; Vlachodimitropoulou, E; ... Sola-Visner, M; + view all (2022) Iron status influences the response of cord blood megakaryocyte progenitors to eltrombopag in vitro. Blood Advances , 6 (1) pp. 13-27. 10.1182/bloodadvances.2021004207. Green open access
file

Llimos, Gerard; Gardeux, Vincent; Koch, Ute; Kribelbauer, Judith F; Hafner, Antonina; Alpern, Daniel; Pezoldt, Joern; ... Deplancke, Bart; + view all (2022) A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation. Nature Communications , 13 (1) , Article 2042. 10.1038/s41467-022-29625-6. Green open access
file

Llombart, V; Mansour, MR; (2022) Therapeutic targeting of "undruggable" MYC. EBioMedicine , 75 , Article 103756. 10.1016/j.ebiom.2021.103756. Green open access
file

Lyskjær, Iben; Kara, Neesha; De Noon, Solange; Davies, Christopher; Rocha, Ana Maia; Strobl, Anna-Christina; Usher, Inga; ... Flanagan, Adrienne M; + view all (2022) Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA. European Journal of Cancer , 168 pp. 1-11. 10.1016/j.ejca.2022.03.002. Green open access
file

M

M, Ahmed; S, Collins; J, Franks; C, Lobo; A, Bacon; L, Paley; SJ, Strauss; (2022) Incidence and Outcome of Breast Sarcomas in England (2013–2018): An analysis from the National Cancer Registration and Analysis Service. European Journal of Cancer , 174 pp. 48-56. 10.1016/j.ejca.2022.06.036. Green open access
file

Macias, Rocio IR; Cardinale, Vincenzo; Kendall, Timothy J; Avila, Matias A; Guido, Maria; Coulouarn, Cedric; Braconi, Chiara; ... Carpino, Guido; + view all (2022) Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions. Gut 10.1136/gutjnl-2022-327099. (In press). Green open access
file

Maciocia, Nicola Christina; (2022) Anti-CD21 Chimeric Antigen Receptor Therapy for the Treatment of T-cell Acute Lymphoblastic Leukaemia. Doctoral thesis (Ph.D), UCL (University College London).

Maciocia, Paul Michael; Wawrzyniecka, Patrycja A; Maciocia, Nicola C; Burley, Amy; Karpanasamy, Thaneswari; Devereaux, Sam; Hoekx, Malika; ... Mansour, Marc R; + view all (2022) Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia. Blood , 140 (1) pp. 25-37. 10.1182/blood.2021013648. Green open access
file

Main, Kavit Harpal Singh; (2022) Targeting Twist: Single Molecule Insights into the Effect of DNA Supercoiling on Topoisomerase Interactions and Topoisomerase Inhibitor Chemotherapeutics. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Mak, Ka-Man; McDonald, Fiona; Teague, Jonathan; Faivre-Finn, Corinne; Forster, Martin; Hanna, Gerard; Moinuddin, Syed; ... Saron, TMG; + view all (2022) SARON: stereotactic ablative radiotherapy for oligometastatic non-small cell lung cancer (NSCLC). Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual. Green open access
file

Malcolm, JC; Falzone, N; Gains, JE; Aldridge, MD; Mirando, D; Lee, BQ; Gaze, MN; (2022) Impact of cyclic changes in pharmacokinetics and absorbed dose in pediatric neuroblastoma patients receiving [177Lu]Lu-DOTATATE. EJNMMI Physics , 9 , Article 24. 10.1186/s40658-022-00436-4. Green open access
file

Malyutina, S; Chervova, O; Tillmann, T; Maximov, V; Ryabikov, A; Gafarov, V; Hubacek, JA; ... Bobak, M; + view all (2022) The Relationship between Epigenetic Age and Myocardial Infarction/Acute Coronary Syndrome in a Population-Based Nested Case-Control Study. Journal of Personalized Medicine , 12 (1) p. 110. 10.3390/jpm12010110. Green open access
file

Marklund, Maja; Schultz, Niklas; Friedrich, Stefanie; Berglund, Emelie; Tarish, Firas; Tanoglidi, Anna; Liu, Yao; ... Lundeberg, Joakim; + view all (2022) Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones. Nature Communications , 13 , Article 5475. 10.1038/s41467-022-33069-3. Green open access
file

Marks, David I; Clifton-Hadley, Laura; Copland, Mhairi; Hussain, Jiaull; Menne, Tobias F; McMillan, Andrew; Moorman, Anthony V; ... Fielding, Adele K; + view all (2022) In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial. Lancet Haematol , 9 (4) e276-e288. 10.1016/S2352-3026(22)00036-9. Green open access
file

Marks, David I; Kirkwood, Amy A; Rowntree, Clare J; Aguiar, Melanie; Bailey, Katharine E; Beaton, Brendan; Cahalin, Paul; ... Fielding, Adele K; + view all (2022) Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial. Lancet Haematology , 9 (4) e262-e275. 10.1016/S2352-3026(22)00038-2. Green open access
file

Marsden, Teresa; McCartan, Neil; Brown, Louise; Rodriguez-Justo, Manuel; Syer, Tom; Brembilla, Giorgio; Van Hemelrijck, Mieke; ... ReIMAGINE Study Group; + view all (2022) The ReIMAGINE prostate cancer risk study protocol: A prospective cohort study in men with a suspicion of prostate cancer who are referred onto an MRI-based diagnostic pathway with donation of tissue, blood and urine for biomarker analyses. PLOS ONE , 17 (2) , Article e0259672. 10.1371/journal.pone.0259672. Green open access
file

Marth, C; Tarnawski, R; Tyulyandina, A; Pignata, S; Gilbert, L; Kaen, D; Rubio, MJ; ... Makker, V; + view all (2022) Phase 3, randomized, open-label study of pembrolizumab plus lenvatinib versus chemotherapy for first-line treatment of advanced or recurrent endometrial cancer: ENGOT-en9/LEAP-001. International journal of gynecological cancer: official journal of the International Gynecological Cancer Society , 32 (1) pp. 93-100. 10.1136/ijgc-2021-003017. Green open access
file

Martins, Filipe Correia; Couturier, Dominique-Laurent; De Santiago, Ines; Sauer, Carolin Margarethe; Vias, Maria; Angelova, Mihaela; Sanders, Deborah; ... Brenton, James D; + view all (2022) Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer. Nature Communications , 13 (1) , Article 6360. 10.1038/s41467-022-33870-0. Green open access
file

Marzolini, Maria AV; Neill, Lorna; O'Reilly, Maeve; Peggs, Karl S; Roddie, Claire; (2022) Lymphocyte morphology in a patient receiving CD19 chimeric antigen receptor T-cell therapy for mantle cell lymphoma. eJHaem , 3 (1) pp. 245-246. 10.1002/jha2.334. Green open access
file

Maughan, Elizabeth F; Hynds, Robert E; Pennycuick, Adam; Nigro, Ersilia; Gowers, Kate HC; Denais, Celine; Gómez-López, Sandra; ... Janes, Sam M; + view all (2022) Cell-intrinsic differences between human airway epithelial cells from children and adults. iScience , 25 (11) , Article 105409. 10.1016/j.isci.2022.105409. Green open access
file

McCourt, Orla; (2022) Exercise during stem cell transplantation for haematological cancer - exploring the feasibility of embedding exercise within a clinical pathway in multiple myeloma. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

McCourt, Orla; Fisher, Abigail; Ramdharry, Gita; Roberts, Anna L; Land, Joanne; Rabin, Neil; Rowe, Katie; (2022) Adaptation of the PERCEPT myeloma prehabilitation trial to virtual delivery: changes in response to the COVID-19 pandemic. BMJ Open , 12 (4) , Article e059516. 10.1136/bmjopen-2021-059516. Green open access
file

McNamara, Mairéad G; Bridgewater, John; Goyal, Lipika; Jacobs, Timothy; Wagner, Anna D; Goldstein, David; Shroff, Rachna; ... Valle, Juan; + view all (2022) What is the gender representation in authorship in later phase systemic clinical trials in biliary tract cancer (BTC)? - a retrospective review of the published literature. BMJ Open , 12 (10) , Article e064954. 10.1136/bmjopen-2022-064954. Green open access
file

Meinhardt, Anna-Lena; Munkhbaatar, Enkhtsetseg; Höckendorf, Ulrike; Dietzen, Michelle; Dechant, Marta; Anton, Martina; Jacob, Anne; ... Jost, Philipp J; + view all (2022) The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner. Oncogene 10.1038/s41388-021-02161-1. (In press). Green open access
file

Meyer, Tim; Caplin, Martyn; Khan, Mohid S; Toumpanakis, Christos; Shetty, Shishir; Ramage, John K; Houchard, Aude; ... Shah, Tahir; + view all (2022) Circulating tumor cells and tumor biomarkers in functional midgut neuroendocrine tumors. Journal of Neuroendocrinology , 34 (4) , Article e13096. 10.1111/jne.13096. Green open access
file

Michelozzi, Ilaria M; Gomez-Castaneda, Eduardo; Pohle, Ruben VC; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Puigdevall-Costa, Pau; Subramaniyam, Meera; ... Giustacchini, Alice; + view all (2022) Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells. Blood Advances 10.1182/bloodadvances.2022008490. (In press). Green open access
file

Miller, Rowan E; Elyashiv, Osnat; El-Shakankery, Karim H; Ledermann, Jonathan A; (2022) Ovarian Cancer Therapy: Homologous Recombination Deficiency as a Predictive Biomarker of Response to PARP Inhibitors. OncoTargets and Therapy , 15 pp. 1105-1117. 10.2147/ott.s272199. Green open access
file

Montinaro, Antonella; Walczak, Henning; (2022) Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries. Cell Death & Differentiation 10.1038/s41418-022-01059-z. (In press). Green open access
file

Morgan, Huw J; Rees, Elise; Lanfredini, Simone; Powell, Kate A; Gore, Jasmine; Gibbs, Alex; Lovatt, Charlotte; ... Patel, Girish K; + view all (2022) CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation , 132 (21) , Article e150750. 10.1172/JCI150750. Green open access
file

Musallam, KM; Taher, AT; Cappellini, MD; Hermine, O; Kuo, KHM; Sheth, S; Viprakasit, V; (2022) Untreated Anemia in Nontransfusion-dependent β-thalassemia: Time to Sound the Alarm. HemaSphere , 6 (12) , Article e806. 10.1097/HS9.0000000000000806. Green open access
file

N

Nageswaran, Gayathri; Byrne, Suzanne; Veeriah, Selvaraju; Chain, Benny; (2022) The Intra-Tumoral T Cell Receptor Repertoire: Steps Towards a Useful Clinical Biomarker. Methods in Molecular Biology , 2574 pp. 135-158. 10.1007/978-1-0716-2712-9_6. Green open access
file

Naidoo, Rosalina; Low, Joseph; Rennoldson, Michael; Danby, Robert; Leonard, Hayley; Madrigal, Alejandro; Lee, Julia; (2022) Variations in provision of psychological care to hematopoietic cell transplant recipients: results of a national survey of UK transplant centers. Bone Marrow Transplantation , 57 pp. 1586-1588. 10.1038/s41409-022-01735-1. Green open access
filefile

Neal, RD; Johnson, P; Clarke, CA; Hamilton, SA; Zhang, N; Kumar, H; Swanton, C; (2022) Cell-Free DNA–Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial. Cancers , 14 (19) , Article 4818. 10.3390/cancers14194818. Green open access
file

Ng, Kevin W; Faulkner, Nikhil; Finsterbusch, Katja; Wu, Mary; Harvey, Ruth; Hussain, Saira; Greco, Maria; ... Kassiotis, George; + view all (2022) SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies. Science Translational Medicine , 14 (655) , Article eabn3715. 10.1126/scitranslmed.abn3715. Green open access
file

Ng, Kien Hoe; (2022) Mapping the MHC-I Immunopeptidome in Solid Tumours: The Impact of Cellular Stress on Antigen Presentation. Doctoral thesis (Ph.D), UCL (University College London).

Nicum, Shibani; Blagden, Sarah P; (2022) PARPs: All for One and One for All? Enhancing Diversity in Clinical Trials. Clinical Cancer Research , 28 (11) pp. 2201-2203. 10.1158/1078-0432.CCR-22-0442. Green open access
file

Nieuwenhuis, Esther A; van Munster, Sanne N; Meijer, Sybren L; Brosens, Lodewijk AA; Jansen, Marnix; Weusten, Bas LAM; Herrero, Lorenza Alvarez; ... Dutch Barrett Expert Centers, .; + view all (2022) Analysis of metastases rates during follow-up after endoscopic resection of early "high-risk" esophageal adenocarcinoma. Gastrointestinal Endoscopy , 96 (2) 237-247.e3. 10.1016/j.gie.2022.03.005. Green open access
file

Northend, M; Wilson, W; Osborne, W; Fox, CP; Davies, AJ; El-Sharkawi, D; Phillips, EH; ... Townsend, WM; + view all (2022) Results of a United Kingdom real-world study of polatuzumab vedotin, bendamustine, and rituximab for relapsed/refractory DLBCL. Blood Advances , 6 (9) pp. 2920-2926. 10.1182/bloodadvances.2021005953. Green open access
file

Nyoni, Lynet; (2022) Targeting the tumour microenvironment through death ligand inhibition. Doctoral thesis (Ph.D), UCL (University College London).

O

O'Malley, David M; Oza, Amit M; Lorusso, Domenica; Aghajanian, Carol; Oaknin, Ana; Dean, Andrew; Colombo, Nicoletta; ... Coleman, Robert L; + view all (2022) Clinical and molecular characteristics of ARIEL3 patients who derived exceptional benefit from rucaparib maintenance treatment for high-grade ovarian carcinoma. Gynecologic Oncology , 167 (3) pp. 404-413. 10.1016/j.ygyno.2022.08.021. Green open access
file

Oaknin, A; Bosse, TJ; Creutzber, CL; Giornelli, G; Harter, P; Joly, F; Lorusso, D; ... ESMO Guidelines Committee, .; + view all (2022) Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology , 33 (9) pp. 860-877. 10.1016/j.annonc.2022.05.009. Green open access
file

Olson, Timothy S; Frost, Benjamin F; Duke, Jamie L; Dribus, Marian; Xie, Hongbo M; Prudowsky, Zachary D; Furutani, Elissa; ... Babushok, Daria; + view all (2022) Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities. JCI Inisight , 7 (22) , Article e163040. 10.1172/jci.insight.163040. Green open access
file

Omer, Omer S; Hertweck, Arnulf; Roberts, Luke B; Lo, Jonathan W; Clough, Jennie N; Jackson, Ian; Pantazi, Eirini D; ... Lord, Graham M; + view all (2022) Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease. Cellular and Molecular Gastroenterology and Hepatology 10.1016/j.jcmgh.2022.05.011. (In press). Green open access
file

Orlando, Francesco; Romanel, Alessandro; Trujillo, Blanca; Sigouros, Michael; Wetterskog, Daniel; Quaini, Orsetta; Leone, Gianmarco; ... Demichelis, Francesca; + view all (2022) Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay. NAR Cancer , 4 (2) , Article zcac016. 10.1093/narcan/zcac016. Green open access
file

Otterstrom, Jason J; Lubin, Alexandra; Payne, Elspeth M; Paran, Yael; (2022) Technologies bringing young Zebrafish from a niche field to the limelight. SLAS Technology 10.1016/j.slast.2021.12.005. (In press). Green open access
file

P

Pagano, Domenico; Home, Philip; Irs, Alar; Ledermann, Jonathan; Curigliano, Giuseppe; Iwatani, Tsuguo; Mandrola, John; (2022) The path for medical associations to sponsor trustworthy guidelines: is it feasible? Journal of the Royal Society of Medicine 10.1177/01410768221095240. (In press). Green open access
file

Palles, Claire; West, Hannah D; Chew, Edward; Galavotti, Sara; Flensburg, Christoffer; Grolleman, Judith E; Jansen, Erik AM; ... de Voer, Richarda M; + view all (2022) Germline MBD4 deficiency causes a multi-tumor predisposition syndrome. American Journal of Human Genetics , 109 (5) pp. 953-960. 10.1016/j.ajhg.2022.03.018. Green open access
file

Pascual, J; Attard, G; Bidard, FC; Curigliano, G; De Mattos-Arruda, L; Diehn, M; Italiano, A; ... Turner, NC; + view all (2022) ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group. Annals of Oncology , 33 (8) pp. 750-768. 10.1016/j.annonc.2022.05.520. Green open access
file

Pearson, AD; Gaspar, N; Janeway, K; Campbell-Hewson, Q; Lawlor, ER; Copland, C; Karres, D; ... Vassal, G; + view all (2022) Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration. European Journal of Cancer , 173 pp. 71-90. 10.1016/j.ejca.2022.06.008. Green open access
file

Petricevic, Branka; Kabiljo, Julijan; Zirnbauer, Rebecca; Walczak, Henning; Laengle, Johannes; Bergmann, Michael; (2022) Neoadjuvant immunotherapy in gastrointestinal cancers - The new standard of care? Seminars in Cancer Biology , 86 (Pt 2) pp. 834-850. 10.1016/j.semcancer.2022.05.015. Green open access
file

Pich, Oriol; Bailey, Chris; Watkins, Thomas BK; Zaccaria, Simone; Jamal-Hanjani, Mariam; Swanton, Charles; (2022) The translational challenges of precision oncology. Cancer Cell , 40 (5) pp. 458-478. 10.1016/j.ccell.2022.04.002. Green open access
file

Pinard, CJ; Tran, WT; Lagree, A; Lu, FI; Klein, J; Oblak, ML; Salgado, R; ... Moore, DA; + view all (2022) Comparative Evaluation of Tumor-Infiltrating Lymphocytes in Companion Animals: Immuno-Oncology as a Relevant Translational Model for Cancer Therapy. Cancers , 14 (20) , Article 5008. 10.3390/cancers14205008. Green open access
file

Pinato, David J; Ferrante, Daniela; Aguilar-Company, Juan; Bower, Mark; Salazar, Ramon; Mirallas, Oriol; Sureda, Anna; ... Cortellini, Alessio; + view all (2022) Vaccination against SARS-CoV-2 protects from morbidity, mortality, and sequelae from COVID19 in patients with cancer. European Journal of Cancer , 171 pp. 64-74. 10.1016/j.ejca.2022.04.036. Green open access
file

Pinato, DJ; Aguilar-Company, J; Ferrante, D; Hanbury, G; Bower, M; Salazar, R; Mirallas, O; ... Chester, J; + view all (2022) Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study. The Lancet Oncology , 23 (7) pp. 865-875. 10.1016/S1470-2045(22)00273-X. Green open access
file

Plummer, R; Dean, E; Arkenau, HT; Redfern, C; Spira, AI; Melear, JM; Chung, KY; ... Shapiro, GI; + view all (2022) A phase 1b study evaluating the safety and preliminary efficacy of berzosertib in combination with gemcitabine in patients with advanced non-small cell lung cancer. Lung Cancer , 163 pp. 19-26. 10.1016/j.lungcan.2021.11.011. Green open access
file

Posor, York; Kampyli, Charis; Bilanges, Benoit; Ganguli, Sushila; Koch, Philipp A; Wallroth, Alexander; Morelli, Daniele; ... Vanhaesebroeck, Bart; + view all (2022) Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover. Developmental Cell 10.1016/j.devcel.2022.06.011. Green open access
file

Poveda, A; Lheureux, S; Colombo, N; Cibula, D; Lindemann, K; Weberpals, J; Bjurberg, M; ... Škof, E; + view all (2022) Olaparib maintenance monotherapy in platinum-sensitive relapsed ovarian cancer patients without a germline BRCA1/BRCA2 mutation: OPINION primary analysis. Gynecologic Oncology 10.1016/j.ygyno.2021.12.025. (In press). Green open access
file

Prêle, Cecilia M; Miles, Tylah; Pearce, David R; O'Donoghue, Robert J; Grainge, Chris; Barrett, Lucy; Birnie, Kimberly; ... Mutsaers, Steven E; + view all (2022) Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis. European Respiratory Journal , 60 (5) , Article 2101469. 10.1183/13993003.01469-2021. Green open access
file

R

Rane, Jayant; Harsanyi, Csilla; Grimes, Helen; Moinuddin, Syed; Quingua, Kristina; Petkar, Shabnam; Dubash, Suraiya; ... Wilson, James; + view all (2022) Tumour location is important in selecting patients who may benefit from abdominal compression when receiving SABR for lung tumours. Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual conference. Green open access
file

Ravichandran, Sriram; Mahmood, Shameem; Wisniowski, Brenden; Sachchithanantham, Sajitha; Popat, Rakesh; Lachmann, Helen; Rabin, Neil; ... D Wechalekar, Ashutosh; + view all (2022) A UK consensus algorithm for early treatment modification in newly diagnosed systemic light-chain amyloidosis. British Journal of Haematology , 198 (2) pp. 328-332. 10.1111/bjh.18216. Green open access
file

Reading, J; Foster, K; Joshi, K; Chain, B; (2022) Tracking down tumor-specific T cells. Cancer Cell , 40 (4) pp. 351-353. 10.1016/j.ccell.2022.03.007. Green open access
file

Reijns, Martin AM; Parry, David A; Williams, Thomas C; Nadeu, Ferran; Hindshaw, Rebecca L; Szwed, Diana O Rios; Nicholson, Michael D; ... Jackson, Andrew P; + view all (2022) Signatures of TOP1 transcription-associated mutagenesis in cancer and germline. Nature , 602 (7898) pp. 623-631. 10.1038/s41586-022-04403-y. Green open access
file

Ren, Zhenggang; Ducreux, Michel; Abou-Alfa, Ghassan K; Merle, Philippe; Fang, Weijia; Edeline, Julien; Li, Zhiwei; ... Cheng, Ann-Lii; + view all (2022) Tislelizumab in Patients with Previously Treated Advanced Hepatocellular Carcinoma (RATIONALE-208): A Multicenter, Non-Randomized, Open-Label, Phase 2 Trial. Liver Cancer 10.1159/000527175. (In press). Green open access
file

Righi, Matteo; Srivastava, Saket; Grothier, Thomas; Robson, Mathew; Kokalaki, Evangelia; Gannon, Isaac; Sillibourne, James; ... Pule, Martin; + view all (2022) Enhancing CAR T Cell Therapy Using Fab Based Constitutively Heterodimeric Cytokine Receptors. Cancer Immunology Research 10.1158/2326-6066.CIR-22-0640. (In press). Green open access
file

Robbe, Pauline; Ridout, Kate E; Vavoulis, Dimitrios V; Dréau, Helene; Kinnersley, Ben; Denny, Nicholas; Chubb, Daniel; ... Schuh, Anna; + view all (2022) Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features. Nature Genetics , 54 pp. 1675-1689. 10.1038/s41588-022-01211-y. Green open access
file

Roddy, H; Meyer, T; Roddie, C; (2022) Novel Cellular Therapies for Hepatocellular Carcinoma. Cancers , 14 (3) , Article 504. 10.3390/cancers14030504. Green open access
file

Rodriguez-Lopez, Maria; Anver, Shajahan; Cotobal, Cristina; Kamrad, Stephan; Malecki, Michal; Correia-Melo, Clara; Hoti, Mimoza; ... Bähler, Jürg; + view all (2022) Correction: Functional profiling of long intergenic non-coding RNAs in fission yeast. [Corrigendum]. eLife , 11 , Article e77337. 10.7554/eLife.77337. Green open access
file

Roncador, Giovanna; Punet-Ortiz, Joan; Maestre, Lorena; Rodriguez-Lobato, Luis Gerardo; Jimenez, Scherezade; Reyes-Garcia, Ana Isabel; Garcia-Gonzalez, Alvaro; ... Engel, Pablo; + view all (2022) CD229 (Ly9) a Novel Biomarker for B-Cell Malignancies and Multiple Myeloma. Cancers , 14 (9) , Article 2154. 10.3390/cancers14092154. Green open access
file

Royal College of Physicians; Royal College of Pathologists; British Society for Genetic Medicine; (2022) Genetic testing in childhood: Guidance for clinical practice. Royal College of Physicians, Royal College of Pathologists and British Society for Genetic Medicine: London, UK.

Royle, KL; Coulson, AB; Ramasamy, K; Cairns, DA; Hockaday, A; Quezada, S; Drayson, M; ... Yong, K; + view all (2022) Risk and response adapted therapy following autologous stem cell transplant in patients with newly diagnosed multiple myeloma (RADAR (UK-MRA Myeloma XV Trial): study protocol for a phase II/III randomised controlled trial. BMJ open , 12 (11) , Article e063037. 10.1136/bmjopen-2022-063037. Green open access
file

S

Sashittal, Palash; Zaccaria, Simone; El-Kebir, Mohammed; (2022) Parsimonious Clone Tree Integration in cancer. Algorithms for Molecular Biology , 17 (1) , Article 3. 10.1186/s13015-022-00209-9. Green open access
file

Satish, P; Freeman, A; Kelly, D; Kirkham, A; Orczyk, C; Simpson, BS; Giganti, F; ... Norris, JM; + view all (2022) Relationship of prostate cancer topography and tumour conspicuity on multiparametric magnetic resonance imaging: a protocol for a systematic review and meta-analysis. BMJ Open , 12 (1) , Article e050376. 10.1136/bmjopen-2021-050376. Green open access
file

Schwarz, G; Banerjee, G; Hostettler, IC; Ambler, G; Seiffge, DJ; Ozkan, H; Browning, S; ... Werring, DJ; + view all (2022) MRI and CT imaging biomarkers of cerebral amyloid angiopathy in lobar intracerebral hemorrhage. International Journal of Stroke 10.1177/17474930211062478. (In press). Green open access
file

Sellar, Rob S; Sperling, Adam S; Słabicki, Mikołaj; Gasser, Jessica A; McConkey, Marie E; Donovan, Katherine A; Mageed, Nada; ... Ebert, Benjamin L; + view all (2022) Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells. Journal of Clinical Investigation , 132 (16) , Article e153514. 10.1172/JCI153514. Green open access
file

Settakorn, K; Kongkarnka, S; Chompupoung, A; Svasti, S; Fucharoen, S; Porter, JB; Srichairatanakool, S; (2022) Effects of green tea extract treatment on erythropoiesis and iron parameters in iron-overloaded β-thalassemic mice. Frontiers in Physiology , 13 , Article 1053060. 10.3389/fphys.2022.1053060. Green open access
file

Sevim, E; Zisa, D; Andrade, D; Sciascia, S; Pengo, V; Tektonidou, MG; Ugarte, A; ... APS ACTION Investigators; + view all (2022) Characteristics of Antiphospholipid Antibody Positive Patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking. Arthritis Care & Research , 74 (2) pp. 324-335. 10.1002/acr.24468. Green open access
file

Sha, M; Kunduzi, B; Froghi, S; Quaglia, A; Davidson, B; Fusai, GK; (2022) Role of circulating exosomal biomarkers and their diagnostic accuracy in pancreatic cancer. JGH Open 10.1002/jgh3.12848. (In press). Green open access
file

Shah, Manish A; Kojima, Takashi; Hochhauser, Daniel; Enzinger, Peter; Raimbourg, Judith; Hollebecque, Antoine; Lordick, Florian; ... Kato, Ken; + view all (2022) T cell-inflamed gene expression profile and PD-L1 expression and pembrolizumab efficacy in advanced esophageal cancer. Future Oncology , 18 (25) pp. 2783-2790. 10.2217/fon-2021-1134. Green open access
file

Shao, SH; Allen, B; Clement, J; Chung, G; Gao, J; Hubbell, E; Liu, MC; ... Tummala, M; + view all (2022) Multi-cancer early detection test sensitivity for cancers with and without current population-level screening options. Tumori 10.1177/03008916221133136. (In press). Green open access
file

Shepherd, DW; Norris, JM; Simpson, BS; Player, DJ; Whitaker, HC; (2022) Effects of Photobiomodulation Therapy on Regulation of Myogenic Regulatory Factor mRNA Expression In Vivo: A Systematic Review. Journal of Biophotonics , 15 (2) , Article e202100219. 10.1002/jbio.202100219. Green open access
file

Sidhu, J; Masurekar, AN; Gogoi, MP; Fong, C; Ioannou, T; Lodhi, T; Parker, C; ... Krishnan, S; + view all (2022) Activity and toxicity of intramuscular 1000 iu/m² polyethylene glycol-E. coli L-asparaginase in the UKALL 2003 and UKALL 2011 clinical trials. British Journal of Haematology 10.1111/bjh.18158. (In press). Green open access
file

Sillibourne, James E; Agliardi, Giulia; Righi, Matteo; Smetanova, Katerina; Rowley, Grant; Speller, Simon; Dolor, Abigail; ... Pule, Martin; + view all (2022) A compact and simple method of achieving differential transgene expression by exploiting translational readthrough. Biotechniques , 72 (4) 10.2144/btn-2021-0079. (In press). Green open access
file

Simpson, Benjamin Scott; (2022) Evaluating novel prognostic biomarkers in prostate cancer. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Singh, Saurabh; Mathew, Manju; Mertzanidou, Thomy; Suman, Shipra; Clemente, Joey; Retter, Adam; Papoutsaki, Marianthi-Vasiliki; ... Punwani, Shonit; + view all (2022) Histo-MRI map study protocol: a prospective cohort study mapping MRI to histology for biomarker validation and prediction of prostate cancer. BMJ Open , 12 (4) , Article e059847. 10.1136/bmjopen-2021-059847. Green open access
file

Smallman-Raynor, MR; Cliff, AD; Robson, SC; Connor, TR; Loman, NJ; Golubchik, T; Martinez Nunez, RT; ... Wong, N; + view all (2022) Spatial growth rate of emerging SARS-CoV-2 lineages in England, September 2020-December 2021. Epidemiology & Infection , 150 , Article e145. 10.1017/S0950268822001285. Green open access
file

Snyder, Alexandra; McGranahan, Nicholas; (2022) The importance of ancestry to understanding tumor mutation burden in cancer. Cancer Cell , 40 (10) pp. 1076-1078. 10.1016/j.ccell.2022.09.004. Green open access
file

Sokač, Mateo; Ahrenfeldt, Johanne; Litchfield, Kevin; Watkins, Thomas BK; Knudsen, Michael; Dyrskjøt, Lars; Jakobsen, Martin R; (2022) Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer. Cancer Research Communications , 2 (8) pp. 762-771. 10.1158/2767-9764.CRC-22-0047. Green open access
file

Spurr, Liam F; Martinez, Carlos A; Katipally, Rohan R; Iyer, Soumya C; Pugh, Sian A; Bridgewater, John A; Primrose, John N; ... Pitroda, Sean P; + view all (2022) A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy. npj Precision Oncology , 6 , Article 72. 10.1038/s41698-022-00318-z. Green open access
file

Stacchiotti, S; Maria Frezza, A; Demetri, GD; Blay, JY; Bajpai, J; Baldi, GG; Baldini, EH; ... Wagner, AJ; + view all (2022) Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments. Cancer Treatment Reviews , 110 , Article 102455. 10.1016/j.ctrv.2022.102455. Green open access
file

Steele, Christopher D; Abbasi, Ammal; Islam, SM Ashiqul; Bowes, Amy L; Khandekar, Azhar; Haase, Kerstin; Hames-Fathi, Shadi; ... Pillay, Nischalan; + view all (2022) Signatures of copy number alterations in human cancer. Nature 10.1038/s41586-022-04738-6. (In press). Green open access
file

Steele, Christopher D; Pillay, Nischalan; Alexandrov, Ludmil B; (2022) An overview of mutational and copy number signatures in human cancer. Journal of Pathology , 257 (4) pp. 454-465. 10.1002/path.5912. Green open access
file

Sudha, Parvathi; Ahsan, Aarif; Ashby, Cody; Kausar, Tasneem; Khera, Akhil; Kazeroun, Mohammad; Hsu, Chih-Chao; ... Walker, Brian A; + view all (2022) MGP Panel is a comprehensive targeted genomics panel for molecular profiling of multiple myeloma patients. Clinical Cancer Research , 28 (13) 2854-2864.. 10.1158/1078-0432.CCR-21-3695. Green open access
file

Sundquist, F; Georgantzi, K; Jarvis, KB; Brok, J; Koskenvuo, M; Rascon, J; van Noesel, M; ... Stenman, J; + view all (2022) A Phase II Trial of a Personalized, Dose-Intense Administration Schedule of 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-Risk Neuroblastoma–LuDO-N. Frontiers in Pediatrics , 10 , Article 836230. 10.3389/fped.2022.836230. Green open access
file

Sutera, Philip; Van Der Eecken, Kim; Kishan, Amar U; Hamid, Anis; Grist, Emily; Attard, Gerhardt; Lotan, Tamara; ... Deek, Matthew P; + view all (2022) Definitions of disease burden across the spectrum of metastatic castration-sensitive prostate cancer: comparison by disease outcomes and genomics. Prostate Cancer and Prostatic Diseases , 25 (4) pp. 713-719. 10.1038/s41391-021-00484-4. Green open access
file

Szmul, Adam; Chandy, Edward; Veiga, Catarina; Jacob, Joseph; Stavropoulou, Alkisti; Landau, David; Hiley, Crispin T; (2022) A Novel and Automated Approach to Classify Radiation Induced Lung Tissue Damage on CT Scans. Cancers , 14 (5) , Article 1341. 10.3390/cancers14051341. Green open access
file

Szyszko, TA; Dunn, JT; Phillips, MM; Bomalaski, J; Sheaff, MT; Ellis, S; Pike, L; ... Szlosarek, PW; + view all (2022) Role of 3'-Deoxy-3'-[¹⁸F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase. JTO Clinical and Research Reports , 3 (9) , Article 100382. 10.1016/j.jtocrr.2022.100382. Green open access
file

T

Taj, MM; Moorman, AV; Hamadeh, L; Petit, A; Asnafi, V; Alby-Laurent, F; Vora, A; ... Macintyre, E; + view all (2022) Prognostic value of Oncogenetic mutations in pediatric T Acute Lymphoblastic Leukemia: a comparison of UKALL2003 and FRALLE2000T protocols. Leukemia , 36 pp. 263-266. 10.1038/s41375-021-01334-x. Green open access
filefile

Tanić, Miljana; Moghul, Ismail; Rodney, Simon; Dhami, Pawan; Vaikkinen, Heli; Ambrose, John; Barrett, James; ... Beck, Stephan; + view all (2022) Comparison and imputation-aided integration of five commercial platforms for targeted DNA methylome analysis. Nature Biotechnology , 40 pp. 1478-1487. 10.1038/s41587-022-01336-9. Green open access
file

Tanner, Lewis E. S.; (2022) Characterising the effect of novel SFK phosphorylation on ADP Ribosylation Factor (ARF) state changes. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Tavares, Manuel; Khandelwal, Garima; Muter, Joanne; Viiri, Keijo; Beltran, Manuel; Brosens, Jan J; Jenner, Richard G; (2022) JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation. Cell Reports , 39 (9) , Article 110889. 10.1016/j.celrep.2022.110889. Green open access
file

Taylor, Alexandra; Sundar, Sudha S; Bowen, Rebecca; Clayton, Rick; Coleridge, Sarah; Fotopoulou, Christina; Ghaem-Maghami, Sadaf; ... Morrison, Jo; + view all (2022) British Gynaecological Cancer Society Recommendations for Women With Gynecological Cancer Who Received Non-standard Care During the COVID-19 Pandemic. Obstetrical and Gynecological Survey , 77 (3) pp. 156-157. 10.1097/01.ogx.0000822432.56370.10. Green open access
file

Teichmann, Sarah A; Haniffa, Muzlifah; Fisher, Jasmin; (2022) Community voices: policy proposals to promote inclusion in academia through the lens of women in science. Nature Communications , 13 , Article 4068. 10.1038/s41467-022-31616-6. Green open access
file

Theobald, Sebastian J; Simonis, Alexander; Mudler, Julie M; Goebel, Ulrike; Acton, Richard; Kohlhas, Viktoria; Albert, Marie-Christine; ... Rybniker, Jan; + view all (2022) Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Molecular Medicine , 14 (8) , Article e15888. 10.15252/emmm.202215888. Green open access
file

Thol, K; Pawlik, P; McGranahan, N; (2022) Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution. Genome Medicine , 14 , Article 137. 10.1186/s13073-022-01138-3. Green open access
file

Tibarewal, Priyanka; Rathbone, Victoria; Constantinou, Georgia; Pearce, Wayne; Adil, Mahreen; Varyova, Zofia; Folkes, Lisa; ... Vanhaesebroeck, Bart; + view all (2022) Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development. The Journal of Pathology 10.1002/path.6009. (In press). Green open access
file

Tisi, Sophie; Dickson, Jennifer L; Horst, Carolyn; Quaife, Samantha L; Hall, Helen; Verghese, Priyam; Gyertson, Kylie; ... SUMMIT Consortium; + view all (2022) Detection of COPD in the SUMMIT Study Lung Cancer Screening Cohort using Symptoms and Spirometry. European Respiratory Journal , 60 (6) , Article 2200795. 10.1183/13993003.00795-2022. Green open access
file

Trujillo, Blanca; Wu, Anjui; Wetterskog, Daniel; Attard, Gerhardt; (2022) Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges. British Journal of Cancer 10.1038/s41416-022-01881-9. (In press). Green open access
file

Turek, Daniel; Haefliger, Simon; Ameline, Baptiste; Alborelli, Ilaria; Calgua, Byron; Hartmann, Wolfgang; Harder, Dorothee; ... Baumhoer, Daniel; + view all (2022) Brown Tumors Belong to the Spectrum of KRAS-driven Neoplasms. The American Journal of Surgical Pathology , 46 (11) pp. 1577-1582. 10.1097/PAS.0000000000001963. Green open access
file

Turri-Zanoni, M; Dalfino, G; Lechner, M; Dallan, I; Battaglia, P; Facco, C; Franzi, F; ... Castelnuovo, P; + view all (2022) Biphenotypic sinonasal sarcoma: European multicentre case-series and systematic literature review. Acta Otorhinolaryngologica Italica , 42 (6) pp. 545-553. 10.14639/0392-100X-N2087. Green open access
file

U

Usher, Inga; Ligammari, Lorena; Ahrabi, Sara; Hepburn, Emily; Connolly, Calum; Bond, Gareth L; Flanagan, Adrienne M; (2022) Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants. Frontiers in Genome Editing , 4 , Article 932434. 10.3389/fgeed.2022.932434. Green open access
file

V

Vanhaesebroeck, Bart; Burke, John E; Madsen, Ralitsa R; (2022) Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation. Cancer Discovery , 12 (1) pp. 20-22. 10.1158/2159-8290.CD-21-1411. Green open access
file

Várnai, Csilla; Palles, Claire; Arnold, Roland; Curley, Helen M; Purshouse, Karin; Cheng, Vinton WT; Booth, Stephen; ... Kurec, Bartlomiej; + view all (2022) Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19. JAMA Network Open , 5 (2) , Article e220130. 10.1001/jamanetworkopen.2022.0130. Green open access
file

Vergote, I; Gonzalez-Martin, A; Lorusso, D; Gourley, C; Mirza, MR; Kurtz, JE; Okamoto, A; ... Zhu, J; + view all (2022) Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup. The Lancet Oncology , 23 (8) e374-e384. 10.1016/S1470-2045(22)00139-5. Green open access
file

Vesely, Clare; Wong, Yien Ning Sophia; Childs, Alexa; Akarca, Ayse U; Dhami, Pawan; Vaikkinen, Heli; Conde, Lucia; ... Meyer, Tim; + view all (2022) Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours. Clinical Cancer Research 10.1158/1078-0432.CCR-21-4203. (In press). Green open access
file

Vicencio, JM; Evans, R; Green, R; An, Z; Deng, J; Treacy, C; Mustapha, R; ... Ng, T; + view all (2022) Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans. Cell Death & Disease , 13 (3) , Article 274. 10.1038/s41419-022-04701-3. Green open access
file

Vithayathil, Mathew; Modolell, Ines; Ortiz-Fernandez-Sordo, Jacobo; Oukrif, Dahmane; Pappas, Apostolos; Januszewicz, Wladyslaw; O'Donovan, Maria; ... di Pietro, Massimiliano; + view all (2022) Image enhanced endoscopy and molecular biomarkers vs Seattle protocol to diagnose dysplasia in Barrett's esophagus. Clinical Gastroenterology and Hepatology 10.1016/j.cgh.2022.01.060. (In press). Green open access
file

Vlachodimitropoulou, E; Garbowski, M; Anne Solomon, S; Abbasi, N; Seaward, G; Windrim, R; Keunen, J; ... Ryan, G; + view all (2022) Outcome predictors for maternal red blood cell alloimmunisation with anti-K and anti-D managed with intrauterine blood transfusion. British Journal of Haematology , 196 (4) pp. 1096-1104. 10.1111/bjh.17956. Green open access
file

Vogl, UM; Beer, TM; Davis, ID; Shore, ND; Sweeney, CJ; Ost, P; Attard, G; ... APCCC 2019 expert panel, .; + view all (2022) Lack of consensus identifies important areas for future clinical research: Advanced Prostate Cancer Consensus Conference (APCCC) 2019 findings. European Journal of Cancer , 160 pp. 24-60. 10.1016/j.ejca.2021.09.036. Green open access
file

W

Wald, Nicholas J; Duffy, Stephen W; Hackshaw, Allan; (2022) When alternatives to screening should be the priority. Journal of Medical Screening , Article ARTN 09691413221102322. 10.1177/09691413221102322. (In press). Green open access
file

Walker, K; Hinsley, S; Phillip, R; Oughton, JB; Murden, G; Chalmers, AJ; Faivre-Finn, C; ... Young, R; + view all (2022) Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations-CONCORDE. JCO Precision Oncology , 6 (6) , Article e2200133. 10.1200/PO.22.00133. Green open access
file

Webster, Amy P; Ecker, Simone; Moghul, Ismail; Dhami, Pawan; Marzi, Sarah; Paul, Dirk S; Kuxhausen, Michelle; ... Beck, Stephan; + view all (2022) Donor whole blood DNA methylation is not a strong predictor of acute graft versus host disease in unrelated donor allogeneic haematopoietic cell transplantation. medRxiv 10.1101/2022.03.08.22272071. (In press). Green open access
file

Weeks, Samuel Luke; (2022) Characterisation of the roles of Stag paralogs in transitions of pluripotency. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Willett, BJ; Grove, J; MacLean, OA; Wilkie, C; De Lorenzo, G; Furnon, W; Cantoni, D; ... Thomson, EC; + view all (2022) SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology 10.1038/s41564-022-01143-7. (In press). Green open access
file

Wilson, MR; Eyre, TA; Kirkwood, AA; Wong Doo, N; Soussain, C; Choquet, S; Martinez-Calle, N; ... McKay, P; + view all (2022) Timing of high-dose methotrexate CNS prophylaxis in DLBCL: a multicenter international analysis of 1384 patients. Blood , 139 (16) pp. 2499-2511. 10.1182/blood.2021014506. Green open access
file

Windsor, Rachael; Hamilton, Anthony; McTiernan, Anne; Dileo, Palma; Michelagnoli, Maria; Seddon, Beatrice; Strauss, Sandra J; (2022) Survival after high-dose chemotherapy for refractory and recurrent Ewing sarcoma. European Journal of Cancer , 170 pp. 131-139. 10.1016/j.ejca.2022.04.007. Green open access
file

Wood, GE; Ledermann, JA; (2022) Adjuvant and post-surgical treatment in high-grade epithelial ovarian cancer. Best Practice & Research Clinical Obstetrics & Gynaecology , 78 pp. 64-73. 10.1016/j.bpobgyn.2021.09.002. Green open access
file

Wray, Jason P; Deltcheva, Elitza M; Boiers, Charlotta; Richardson, Simon Е; Chhetri, Jyoti Bikram; Brown, John; Gagrica, Sladjana; ... Enver, Tariq; + view all (2022) Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability. Nature Communications , 13 , Article 7124. 10.1038/s41467-022-34653-3. Green open access
file

Wright, DW; Harvey, WT; Hughes, J; Cox, M; Peacock, TP; Colquhoun, R; Jackson, B; ... Hassan-Ibrahim, MO; + view all (2022) Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer. Virus Evolution , 8 (1) , Article veac023. 10.1093/ve/veac023. Green open access
file

Wu, Honghan; Wang, Minhong; Wu, Jinge; Francis, Farah; Chang, Yun-Hsuan; Shavick, Alex; Dong, Hang; ... Dobson, Richard JB; + view all (2022) A survey on clinical natural language processing in the United Kingdom from 2007 to 2022. npj Digital Medicine , 5 , Article 186. 10.1038/s41746-022-00730-6. Green open access
file

Wu, M; Shen, H; Wang, Z; Kanu, N; Chen, K; (2022) Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer. Chronic Diseases and Translational Medicine 10.1002/cdt3.10. Green open access
file

Wu, Mary Y; Carr, Edward J; Harvey, Ruth; Mears, Harriet V; Kjaer, Svend; Townsley, Hermaleigh; Hobbs, Agnieszka; ... Bauer, David LV; + view all (2022) WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed. The Lancet , 400 (10369) pp. 2193-2196. 10.1016/s0140-6736(22)01938-9. Green open access
file

Wu, Wenyi; Ma, Gaoen; Qi, Hui; Dong, Lijun; Chen, Fang; Wang, Yun; Mao, Xingxing; ... Lei, Hetian; + view all (2022) Genome Editing of Pik3cd Impedes Abnormal Retinal Angiogenesis. Human Gene Therapy 10.1089/hum.2022.079. (In press). Green open access
file

Wu, Yin; Biswas, Dhruva; Usaite, Ieva; Angelova, Mihaela; Boeing, Stefan; Karasaki, Takahiro; Veeriah, Selvaraju; ... Swanton, Charles; + view all (2022) A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer. Nature Cancer , 3 pp. 696-709. 10.1038/s43018-022-00376-z. Green open access
file

X

Xu, Ke; Childerhouse, Anna; Gupta, Rajeev; (2022) Burkitt leukaemia with B-cell precursor immunophenotype. eJHaem , 3 (3) pp. 1044-1045. 10.1002/jha2.450. Green open access
file

Y

Yngvadottir, Bryndis; Andreou, Avgi; Bassaganyas, Laia; Larionov, Alexey; Cornish, Alex J; Chubb, Daniel; Saunders, Charlie N; ... Maher, Eamonn R; + view all (2022) Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases. Human Molecular Genetics , Article ddac089. 10.1093/hmg/ddac089. (In press). Green open access
file

Yong, K; Wilson, W; de Tute, RM; Camilleri, M; Ramasamy, K; Streetly, M; Sive, J; ... Popat, R; + view all (2022) Upfront autologous haematopoietic stem-cell transplantation versus carfilzomib–cyclophosphamide–dexamethasone consolidation with carfilzomib maintenance in patients with newly diagnosed multiple myeloma in England and Wales (CARDAMON): a randomised, phase 2, non-inferiority trial. The Lancet Haematology , 10 (2) e93-e106. 10.1016/S2352-3026(22)00350-7. Green open access
file

Yousefi, Maryam; Boross, Gábor; Weiss, Carly; Murray, Christopher W; Hebert, Jess D; Cai, Hongchen; Ashkin, Emily L; ... Winslow, Monte M; + view all (2022) Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer Research , 82 (8) pp. 1589-1602. 10.1158/0008-5472.CAN-22-0059. Green open access
file

Z

Zachara, Magda; Rainer, Pernille Y; Hashimi, Horia; Russeil, Julie M; Alpern, Daniel; Ferrero, Radiana; Litovchenko, Maria; (2022) Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner. The EMBO Journal , Article e108206. 10.15252/embj.2021108206. (In press). Green open access
file

Zakeri, N; Hall, A; Swadling, L; Pallett, LJ; Schmidt, NM; Diniz, MO; Kucykowicz, S; ... Maini, MK; + view all (2022) Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma. Nature Communications , 13 , Article 1372. 10.1038/s41467-022-29012-1. Green open access
file

Zammarchi, Francesca; Havenith, Karin Eg; Chivers, Simon; Hogg, Paul; Bertelli, Francois; Tyrer, Peter; Janghra, Narinder; ... van Berkel, Patrick H; + view all (2022) Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers. Molecular Cancer Therapeutics , 21 (4) pp. 582-593. 10.1158/1535-7163.MCT-21-0715. Green open access
file

Zhai, Haoran; (2022) Investigating the role of genomic alterations and altered DNA replication timing during malignant transformation in tumours. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Zhang, H; AbdulJabbar, K; Grunewald, T; Akarca, A; Hagos, Y; Lecat, C; Pate, D; ... Yuan, Y; + view all (2022) Self-supervised Antigen Detection Artificial Intelligence (SANDI). In: Xu, X and Li, X and Mahapatra, D and Cheng, L and Petitjean, C and Fu, H, (eds.) Resource-Efficient Medical Image Analysis: First MICCAI Workshop, REMIA 2022, Singapore, September 22, 2022, Proceedings. (pp. pp. 12-21). Springer: Cham, Switzerland. Green open access
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Zhang, Xiaoyan; Yang, Ling; Lei, Wanjun; Hou, Qiang; Huang, Ming; Zhou, Rongjing; Enver, Tariq; (2022) Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer. EBioMedicine , 82 , Article 104125. 10.1016/j.ebiom.2022.104125. Green open access
file

Zhao, Yi; Simpson, Benjamin S; Morka, Naomi; Freeman, Alex; Kirkham, Alex; Kelly, Daniel; Whitaker, Hayley C; ... Norris, Joseph M; + view all (2022) Comparison of Multiparametric Magnetic Resonance Imaging with Prostate-Specific Membrane Antigen Positron-Emission Tomography Imaging in Primary Prostate Cancer Diagnosis: A Systematic Review and Meta-Analysis. Cancers , 14 (14) , Article 3497. 10.3390/cancers14143497. Green open access
file

Zhou, C; O'Connor, J; Backen, A; Valle, JW; Bridgewater, J; Dive, C; Jayson, GC; (2022) Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers. ESMO Open , 7 (2) , Article 100417. 10.1016/j.esmoop.2022.100417. Green open access
file

Zhu, Tianyu; Liu, Jacklyn; Beck, Stephan; Pan, Sun; Capper, David; Lechner, Matt; Thirlwell, Chrissie; ... Teschendorff, Andrew E; + view all (2022) A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution. Nature Methods , 19 pp. 296-306. 10.1038/s41592-022-01412-7. Green open access
file

Zinngrebe, Julia; Moepps, Barbara; Monecke, Thomas; Gierschik, Peter; Schlichtig, Ferdinand; Barth, Thomas FE; Strauß, Gudrun; ... Debatin, Klaus-Michael; + view all (2022) Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS. EMBO Molecular Medicine , 14 (3) , Article e14901. 10.15252/emmm.202114901. Green open access
file

Znati, Sami; (2022) A Translational Study of Vandetanib Treatment for Hepatocellular Carcinoma. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Sun Oct 20 23:40:20 2024 BST.