Wang, Tao; (2018) Essays on Technological Innovation in the Health Care Industry. Doctoral thesis (Ph.D), UCL (University College London).

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Abstract

This thesis investigates the relationship between knowledge management and innovation performance in the context of new product development in the biotechnology industry. The dissertation contains three empirical essays in three different research settings. Chapter two focuses on how to improve the outcome-dependence of experiential learning. The findings demonstrate that two innovation strategy choices - the novelty of innovation and the primary ownership - enable prior failure experience to reduce the incidence of future failure more than prior success experience does. Chapter three assesses stage specific learning and knowledge spillover. The findings demonstrate that the productivity of drug research increases only with previous upstream research experience, whereas the productivity of drug development increases only with previous downstream development experience. Chapter four investigates the interaction between network structure and interfirm governance and its effect on knowledge appropriation and innovation behaviour. The findings show that interfirm governance contingently determines the outcome of patent applications and patent citations within a dense network. Together these three essays provide three primary contributions. First, the dissertation shows that failure experience has knowledge benefits and investing in failures allows an organisation to build capabilities that improve future performance. In addition, two innovation strategies - innovation novelty and primary ownership - moderate the search behaviour and help to translate the inferences from an organisational experience into knowledge and routines. Second, the dissertation illustrates that both learning by doing and product innovation explain economic growth externality and improve productivity, and knowledge spillover is bounded in the same stage for long-run growth. Third, when considering the formation of alliances to advance innovation, neither alliance network structure nor interfirm governance guarantee superior performance. Therefore, the dynamic process of a strategic alliance by focusing on the interaction between network structure and interfirm governance need to be considered.

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