James, E;
Powell, S;
Munro, P;
(2021)
Simulation of statistically accurate time-integrated dynamic speckle patterns in biomedical optics.
Optics Letters
, 46
(17)
pp. 4390-4393.
10.1364/OL.435812.
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Abstract
The simulation of statistically accurate time-integrated dynamic speckle patterns using a physics-based model that accounts for spatially varying sample properties is yet to be presented in biomedical optics. In this Letter, we propose a solution to this important problem based on the Karhunen–Loève expansion of the electric field and apply our method to the formalisms of both laser speckle contrast imaging and diffuse correlation spectroscopy. We validate our technique against solutions for speckle contrast for different forms of homogeneous field and also show that our method can readily be extended to cases with spatially varying sample properties.
| Type: | Article |
|---|---|
| Title: | Simulation of statistically accurate time-integrated dynamic speckle patterns in biomedical optics |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/OL.435812 |
| Publisher version: | https://doi.org/10.1364/OL.435812 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10132807 |
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