Morris, TJ;
Beck, S;
(2015)
Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.
Methods
, 72
3 - 8.
10.1016/j.ymeth.2014.08.011.
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Abstract
The Illumina HumanMethylation450 BeadChip has become a popular platform for interrogating DNA methylation in epigenome-wide association studies (EWAS) and related projects as well as resource efforts such as the International Cancer Genome Consortium (ICGC) and the International Human Epigenome Consortium (IHEC). This has resulted in an exponential increase of 450k data in recent years and triggered the development of numerous integrated analysis pipelines and stand-alone packages. This review will introduce and discuss the currently most popular pipelines and packages and is particularly aimed at new 450k users.
| Type: | Article |
|---|---|
| Title: | Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ymeth.2014.08.011 |
| Publisher version: | http://dx.doi.org/10.1016/j.ymeth.2014.08.011 |
| Language: | English |
| Additional information: | Copyright © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). |
| Keywords: | 450k BeadChip, Analysis pipelines, DNA methylation, EWAS, Epigenetics, HumanMethylation450 |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/1450650 |
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