Browse by UCL Departments and Centres
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Number of items: 30.
A
Alić, I;
Goh, PA;
Murray, A;
Portelius, E;
Gkanatsiou, E;
Gough, G;
Mok, KY;
... Nižetić, D; + view all
(2020)
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Molecular Psychiatry
10.1038/s41380-020-0806-5.
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Altendahl, M;
Cotter, DL;
Staffaroni, AM;
Wolf, A;
Mumford, P;
Cobigo, Y;
Casaletto, K;
... Walsh, CM; + view all
(2020)
REM sleep is associated with white matter integrity in cognitively healthy, older adults.
PLoS One
, 15
(7)
, Article e0235395. 10.1371/journal.pone.0235395.
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Area-Gomez, E;
Larrea, D;
Pera, M;
Agrawal, RR;
Guilfoyle, DN;
Pirhaji, L;
Shannon, K;
... Nuriel, T; + view all
(2020)
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.
Scientific Reports
, 10
, Article 4277. 10.1038/s41598-020-61142-8.
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B
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Bartels, T;
De Schepper, S;
Hong, S;
(2020)
Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
Science
, 370
(6512)
pp. 66-69.
10.1126/science.abb8587.
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Busche, MA;
Hyman, BT;
(2020)
Synergy between amyloid-β and tau in Alzheimer's disease.
Nature Neuroscience
, 23
pp. 1183-1193.
10.1038/s41593-020-0687-6.
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C
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Cannavo, C;
Tosh, J;
Fisher, EMC;
Wiseman, FK;
(2020)
Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21.
In: Dierssen, M, (ed.)
Progress in Brain Research.
(pp. 181-208).
Elsevier: London, UK.
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Chang, P;
Bush, D;
Schorge, S;
Good, M;
Canonica, T;
Shing, N;
Noy, S;
... Fisher, EMC; + view all
(2020)
Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome.
Cell Reports
, 30
(4)
1152-1163.e4.
10.1016/j.celrep.2019.12.065.
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Chen, W-T;
Lu, A;
Craessaerts, K;
Pavie, B;
Sala Frigerio, C;
Corthout, N;
Qian, X;
... De Strooper, B; + view all
(2020)
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Cell
, 182
(4)
976-991.e19.
10.1016/j.cell.2020.06.038.
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Cisneros, E;
di Marco, F;
Rueda-Carrasco, J;
Lillo, C;
Pereyra, G;
Martín-Bermejo, MJ;
Vargas, A;
... Bovolenta, P; + view all
(2020)
Sfrp1 deficiency makes retinal photoreceptors prone to degeneration.
Scientific Reports
, 10
(1)
, Article 5115. 10.1038/s41598-020-61970-8.
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Couedic, TL;
Caillon, R;
Rossant, F;
Joutel, A;
Urien, H;
Rajani, RM;
(2020)
Deep-learning based segmentation of challenging myelin sheaths.
In:
2020 Tenth International Conference on Image Processing Theory, Tools and Applications (IPTA).
IEEE: Paris, France.
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F
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Foiani, Martha;
(2020)
Investigating novel tau biomarkers for frontotemporal dementia.
Doctoral thesis (Ph.D), UCL (University College London).
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Fung, CW;
Guo, J;
Fu, H;
Figueroa, HY;
Konofagou, EE;
Duff, KE;
(2020)
Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy.
Science Advances
, 6
(42)
, Article eabc8098. 10.1126/sciadv.abc8098.
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G
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Glennon, EB;
Lau, DHW;
Gabriele, RMC;
Taylor, MF;
Troakes, C;
Opie-Martin, S;
Elliott, C;
... Noble, W; + view all
(2020)
Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release.
Brain Communications
, 2
(1)
, Article fcaa011. 10.1093/braincomms/fcaa011.
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Guerrero, A;
Guiho, R;
Herranz, N;
Uren, A;
Withers, DJ;
Martínez-Barbera, JP;
Tietze, LF;
(2020)
Galactose-modified duocarmycin prodrugs as senolytics.
Aging Cell
, Article e13133. 10.1111/acel.13133.
(In press).
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H
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Harris, SS;
Wolf, F;
De Strooper, B;
Busche, MA;
(2020)
Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer's Disease.
Neuron
, 107
(3)
pp. 417-435.
10.1016/j.neuron.2020.06.005.
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Heller, C;
Chan, E;
Foiani, MS;
Todd, E;
Russell, LL;
Greaves, CV;
Heslegrave, AJ;
... Rohrer, JD; + view all
(2020)
Plasma glial fibrillary acidic protein and neurofilament light chain are measures of disease severity in semantic variant primary progressive aphasia.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2020-325085.
(In press).
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Heller, C;
Foiani, MS;
Moore, K;
Convery, R;
Bocchetta, M;
Neason, M;
Cash, DM;
... GENFI; + view all
(2020)
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2019-321954.
(In press).
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Hithersay, R;
Baksh, RA;
Startin, CM;
Wijeratne, P;
Hamburg, S;
Carter, B;
LonDownS Consortium;
(2020)
Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndrome.
Alzheimer's & Dementia
10.1002/alz.12222.
(In press).
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K
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Kyrargyri, V;
Madry, C;
Rifat, A;
Arancibia-Carcamo, IL;
Jones, SP;
Chan, VTT;
Xu, Y;
... Attwell, D; + view all
(2020)
P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1β release.
Glia
, 68
(2)
pp. 328-344.
10.1002/glia.23719.
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L
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Leija Salazar, Melissa Ivonne;
(2020)
Investigation of somatic mutations in synucleinopathies.
Doctoral thesis (Ph.D), UCL (University College London).
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M
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Ma, D;
Cardoso, MJ;
Zuluaga, MA;
Modat, M;
Powell, NM;
Wiseman, FK;
Cleary, JO;
... Ourselin, SE; + view all
(2020)
Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome – a comprehensive morphometric analysis with active staining contrast-enhanced MRI.
NeuroImage
, 223
, Article 117271. 10.1016/j.neuroimage.2020.117271.
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P
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Pigoni, M;
Hsia, H-E;
Hartmann, J;
Rudan Njavro, J;
Shmueli, MD;
Müller, SA;
Güner, G;
... Lichtenthaler, SF; + view all
(2020)
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
The EMBO Journal
, 2020
, Article e103457. 10.15252/embj.2019103457.
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Q
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Quick, S;
Moss, J;
Rajani, RM;
Williams, A;
(2020)
A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease.
Trends in Neurosciences
10.1016/j.tins.2020.11.003.
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R
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Rodriguez, GA;
Barrett, GM;
Duff, KE;
Hussaini, SA;
(2020)
Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus.
PLoS Biology
, 18
(8)
, Article e3000851. 10.1371/journal.pbio.3000851.
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Rueda-Carrasco, J;
Hong, S;
(2020)
The Jekyll and Hyde of TREM2.
Trends Neurosciences
, 43
(10)
pp. 739-740.
10.1016/j.tins.2020.08.002.
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S
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Sanderson, JB;
De, S;
Jiang, H;
Rovere, M;
Jin, M;
Zaccagnini, L;
Hays Watson, A;
... Bartels, T; + view all
(2020)
Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies.
Brain Communications
, 2
(1)
, Article fcaa010. 10.1093/braincomms/fcaa010.
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Sierksma, A;
Lu, A;
Mancuso, R;
Fattorelli, N;
Thrupp, N;
Salta, E;
Zoco, J;
... Fiers, M; + view all
(2020)
Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology.
EMBO Molecular Medicine
, Article e10606. 10.15252/emmm.201910606.
(In press).
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Startin, CM;
D'Souza, H;
Ball, G;
Hamburg, S;
Hithersay, R;
Hughes, KMO;
Massand, E;
... Strydom, A; + view all
(2020)
Health comorbidities and cognitive abilities across the lifespan in Down syndrome.
Journal of Neurodevelopmental Disorders
, 12
, Article 4. 10.1186/s11689-019-9306-9.
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T
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Thomas, MSC;
Ojinaga Alfageme, O;
D'Souza, H;
Patkee, PA;
Rutherford, MA;
Mok, KY;
Hardy, J;
... LonDownS Consortium; + view all
(2020)
A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment.
Research in Developmental Disabilities
, 104
, Article 103638. 10.1016/j.ridd.2020.103638.
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Thrupp, N;
Sala Frigerio, C;
Wolfs, L;
Skene, NG;
Fattorelli, N;
Poovathingal, S;
Fourne, Y;
... Fiers, M; + view all
(2020)
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans.
Cell Reports
, 32
(13)
, Article 108189. 10.1016/j.celrep.2020.108189.
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