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Article

Abbosh, C; Swanton, C; (2021) ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors. PLoS Medicine , 18 (10) , Article e1003771. 10.1371/journal.pmed.1003771. Green open access
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Abdul-Jawad, S; Baù, L; Alaguthurai, T; Del Molino Del Barrio, I; Laing, AG; Hayday, TS; Monin, L; ... Irshad, S; + view all (2021) Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients. Cancer Cell 10.1016/j.ccell.2021.01.001. (In press). Green open access
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Adams, RA; Fisher, DJ; Graham, J; Seligmann, JF; Seymour, M; Kaplan, R; Yates, E; ... FOCUS4 Trial Investigators; + view all (2021) Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. Journal of clinical oncology: official journal of the American Society of Clinical Oncology 10.1200/JCO.21.01436. (In press). Green open access
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Agliardi, G; Liuzzi, AR; Hotblack, A; De Feo, D; Núñez, N; Stowe, CL; Friebel, E; ... Becher, B; + view all (2021) Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nature Communications , 12 , Article 444. 10.1038/s41467-020-20599-x. Green open access
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Ahmed, Mahbubl; Collins, Shane; Bacon, Andrew; Franks, Joanna; Lobo, Cheryl; Paley, Lizz; Strauss, Sandra; (2021) 08. Incidence and outcome of breast sarcomas in NHS England (2013-2018): An analysis from Public Health England (PHE) National Cancer Registration and Analysis Service (NCRAS). European Journal of Surgical Oncology , 47 (5) e288-e288. 10.1016/j.ejso.2021.03.204. Green open access
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Ainley, L; Chavda, SJ; Counsell, N; Cheesman, S; Newrick, F; Horder, J; Kyriakou, C; ... Yong, K; + view all (2021) DT‐PACE/ESHAP chemotherapy regimens as salvage therapy for multiple myeloma prior to autologous stem cell transplantation. British Journal of Haematology , 192 (3) e73-e77. 10.1111/bjh.17248. Green open access
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Akay, M; Funingana, I-G; Patel, G; Mustapha, R; Gjafa, E; Ng, T; Ng, K; (2021) An In-Depth Review of Niraparib in Ovarian Cancer: Mechanism of Action, Clinical Efficacy and Future Directions. Oncology and Therapy 10.1007/s40487-021-00167-z. (In press). Green open access
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Alhawaj, A; (2021) Stem Cell-Based Therapy for Hirschsprung Disease, Do We Have the Guts to Treat? Gene Therapy 10.1038/s41434-021-00268-4. (In press). Green open access
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Ali, A; Hoyle, AP; Parker, CC; Brawley, CD; Cook, A; Amos, C; Calvert, J; ... STAMPEDE investigators; + view all (2021) Bone metastatic burden as a predictor of survival benefit from prostate radiotherapy in newly-diagnosed metastatic prostate cancer. JAMA oncology , 7 (4) pp. 555-563. 10.1001/jamaoncol.2020.7857. Green open access
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Alliouachene, S; Kieswich, JE; Bilanges, B; McCafferty, K; Thiemermann, C; Vanhaesebroeck, B; Yaqoob, MM; (2021) Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice. American Journal of Transplantation 10.1111/ajt.16470. (In press). Green open access
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Almarzouki, A; Wilson, D; Ambler, G; Shakeshaft, C; Cohen, H; Yousry, T; Al-Shahi Salman, R; ... Werring, DJ; + view all (2021) Publisher Correction: Sensitivity and specificity of blood-fluid levels for oral anticoagulant-associated intracerebral haemorrhage. Scientific Reports , 11 (1) , Article 9485. 10.1038/s41598-021-88890-5. Green open access
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Alsulami, AF; Torres, PHM; Moghul, I; Arif, SM; Chaplin, AK; Vedithi, SC; Blundell, TL; (2021) COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets. Briefings in Bioinformatics , 22 (6) , Article bbab220. 10.1093/bib/bbab220. Green open access
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Alsulami, AF; Thomas, SE; Jamasb, AR; Beaudoin, CA; Moghul, I; Bannerman, B; Copoiu, L; ... Blundell, TL; + view all (2021) SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets. Briefings in Bioinformatics , 22 (2) pp. 769-780. 10.1093/bib/bbaa404. Green open access
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Alwan, Ferras; Vendramin, Chiara; Budde, Ulrich; Liesner, Ri; Taylor, Alice; Thomas, Mari; Lämmle, Bernhard; (2021) Assessing thrombogenesis and treatment response in congenital thrombotic thrombocytopenic purpura. EJHaem , 2 (2) pp. 188-195. 10.1002/jha2.178. Green open access
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Anquetil, T; Solinhac, R; Jaffre, A; Chicanne, G; Viaud, J; Darcourt, J; Orset, C; ... Gratacap, M-P; + view all (2021) PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity. EMBO Reports , 22 (6) , Article e51299. 10.15252/embr.202051299. Green open access
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Arend, RC; Monk, BJ; Herzog, TJ; Moore, KN; Shapira-Frommer, R; Ledermann, JA; Tewari, KS; ... Penson, RT; + view all (2021) Utilizing an interim futility analysis of the OVAL study (VB-111-701/GOG 3018) for potential reduction of risk: A phase III, double blind, randomized controlled trial of ofranergene obadenovec (VB-111) and weekly paclitaxel in patients with platinum resistant ovarian cancer. Gynecologic Oncology , 161 (2) pp. 496-501. 10.1016/j.ygyno.2021.02.014. Green open access
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Arshad, R; Tabish, TA; Kiani, MH; Ibrahim, IM; Shahnaz, G; Rahdar, A; Kang, M; (2021) A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection. Nanomaterials , 11 (5) , Article 1086. 10.3390/nano11051086. Green open access
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Ascierto, PA; Blank, C; Dummer, R; Ernstoff, MS; Ferrone, S; Fox, BA; Gajewski, TF; ... Thurin, M; + view all (2021) Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy). Journal of Translational Medicine , 19 , Article 278. 10.1186/s12967-021-02951-x. Green open access
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Attard, G; Brown, LC; Clarke, NW; Parmar, MKB; James, ND; (2021) Should Patients with High-risk Localised or Locally Advanced Prostate Cancer Receive Abiraterone Acetate in Addition to Androgen Deprivation Therapy? Update on a Planned Analysis of the STAMPEDE Trial. European Urology , 80 (4) pp. 522-523. 10.1016/j.eururo.2021.06.023. Green open access
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Attard, G; Murphy, L; Clarke, NW; Cross, W; Jones, RJ; Parker, CC; Gillessen, S; ... Systemic Therapy in Advancing or Metastatic Prostate cancer: Eva; + view all (2021) Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol. The Lancet 10.1016/S0140-6736(21)02437-5. (In press). Green open access
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Au, L; Hatipoglu, E; Robert de Massy, M; Litchfield, K; Beattie, G; Rowan, A; Schnidrig, D; ... TRACERx Renal Consortium; + view all (2021) Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma. Cancer Cell , 39 pp. 1497-1518. 10.1016/j.ccell.2021.10.001. Green open access
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Au, L; Fendler, A; Shepherd, STC; Rzeniewicz, K; Cerrone, M; Byrne, F; Carlyle, E; ... Turajlic, S; + view all (2021) Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2. Nature Medicine 10.1038/s41591-021-01387-6. Green open access
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Avenoso, D; Marsh, JCW; Potter, V; Pagliuca, A; Slade, S; Dignan, F; Tholouli, E; ... Kulasekararaj, AG; + view all (2021) SARS-CoV-2 infection in aplastic anaemia. Haematologica 10.3324/haematol.2021.279928. (In press). Green open access
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Azzoni, E; Frontera, V; Anselmi, G; Rode, C; James, C; Deltcheva, EM; Demian, AS; ... de Bruijn, MFTR; + view all (2021) The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition. Cell Reports , 37 (11) , Article 110103. 10.1016/j.celrep.2021.110103. Green open access
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Bachy, E; Rufibach, K; Parreira, J; Launonen, A; Nielsen, T; Hackshaw, A; (2021) Phase III Clinical Trials in First-Line Follicular Lymphoma: A Review of Their Design and Interpretation. Advances in Therapy 10.1007/s12325-021-01738-2. (In press). Green open access
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Baert, T; Ferrero, A; Sehouli, J; O Donnell, DM; González-Martín, A; Joly, F; Van der Velden, J; ... Ledermann, JA; + view all (2021) The systemic treatment of recurrent ovarian cancer revisited. Annals of Oncology , 32 (6) pp. 710-725. 10.1016/j.annonc.2021.02.015. Green open access
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Bailey, C; Black, JRM; Reading, JL; Litchfield, K; Turajlic, S; McGranahan, N; Jamal-Hanjani, M; (2021) Tracking Cancer Evolution through the Disease Course. Cancer Discovery , 11 (4) pp. 916-932. 10.1158/2159-8290.CD-20-1559. Green open access
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Balestrini, S; Koepp, MJ; Gandhi, S; Rickman, HM; Yen Shin, G; Houlihan, CF; Anders-Cannon, J; ... Sisodiya, SM; + view all (2021) Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy. Epilepsy & Behavior , 115 , Article 107602. 10.1016/j.yebeh.2020.107602. Green open access
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Banfill, K; Croxford, W; Fornacon-Wood, I; Wicks, K; Ahmad, S; Britten, A; Carson, C; ... Faivre-Finn, C; + view all (2021) Changes in the Management of Patients having Radical Radiotherapy for Lung Cancer during the First Wave of the COVID-19 Pandemic in the UK. Clinical Oncology 10.1016/j.clon.2021.10.009. (In press). Green open access
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Barmpoutis, P; Di Capite, M; Kayhanian, H; Waddingham, W; Alexander, DC; Jansen, M; Kwong, FNK; (2021) Tertiary lymphoid structures (TLS) identification and density assessment on H&E-stained digital slides of lung cancer. PLOS ONE , 16 (9) , Article e0256907. 10.1371/journal.pone.0256907. Green open access
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Bartlett, JMS; Bayani, J; Kornaga, E; Xu, K; Pond, GR; Piper, T; Mallon, E; ... Rea, D; + view all (2021) Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study. NPJ Breast Cancer , 7 (1) , Article 90. 10.1038/s41523-021-00297-7. Green open access
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Batty, Paul; Riddell, Anne; Kitchen, Steve; Sardo Infirri, Sofia; Walker, Isobel; Woods, Tim; Jennings, Ian; (2021) Factor VIII/IX inhibitor testing practices in the United Kingdom: Results of a UKHCDO and UKNEQAS national survey. Haemophilia , 27 (3) pp. 490-499. 10.1111/hae.14158. Green open access
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Baumhoer, D; Haefliger, S; Ameline, B; Hartmann, W; Amary, F; Cleven, A; Klein, MJ; ... O'Donnell, P; + view all (2021) Ossifying Fibroma of Non-odontogenic Origin: A Fibro-osseous Lesion in the Craniofacial Skeleton to be (Re-)considered. Head and Neck Pathology 10.1007/s12105-021-01351-3. (In press). Green open access
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Bekaii-Saab, TS; Bridgewater, J; Normanno, N; (2021) Practical considerations in screening for genetic alterations in cholangiocarcinoma. Annals of Oncology 10.1016/j.annonc.2021.04.012. (In press). Green open access
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Ben-Yosef, N; Frampton, M; Schiff, ER; Daher, S; Abu Baker, F; Safadi, R; Israeli, E; ... Levine, AP; + view all (2021) Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease. Gastroenterology Report , 9 (6) pp. 521-532. 10.1093/gastro/goab007. Green open access
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Benjamin, LA; Paterson, RW; Moll, R; Pericleous, C; Brown, R; Mehta, PR; Athauda, D; ... Efthymiou, M; + view all (2021) Antiphospholipid antibodies and neurological manifestations in acute COVID-19: A single-centre cross-sectional study. EClinicalMedicine , Article 101070. 10.1016/j.eclinm.2021.101070. (In press). Green open access
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Bennett, CL; (2021) Switching between tolerance and immunity: Do counter-acting gene networks dictate Langerhans cell function in the skin? BioEssays , 43 (5) , Article 2100072. 10.1002/bies.202100072. Green open access
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Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; ... McGranahan, N; + view all (2021) Using DNA sequencing data to quantify T cell fraction and therapy response. Nature , 597 pp. 555-560. 10.1038/s41586-021-03894-5. Green open access
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Bertaglia, V; Reale, ML; Bironzo, P; Palesandro, E; Mariniello, A; Leone, G; Tabbò, F; ... Novello, S; + view all (2021) Italian survey on the clinical management of non-small cell lung cancer patients during the COVID-19 pandemic: A lesson for the second wave. Critical Reviews in Oncology/Hematology , 157 , Article 103189. 10.1016/j.critrevonc.2020.103189. Green open access
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Best, JG; Ambler, G; Wilson, D; Lee, K-J; Lim, J-S; Shiozawa, M; Koga, M; ... Werring, DJ; + view all (2021) Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. The Lancet Neurology , 20 (4) pp. 294-303. 10.1016/S1474-4422(21)00024-7. Green open access
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Best, J; Starkey, T; Chaterjee, A; Fackrell, D; Pettit, L; Srihari, N; Tween, H; ... Lee, LYW; + view all (2021) Coronavirus Disease 2019: the Pivotal Role of UK Clinical Oncology and the UK Coronavirus Cancer Monitoring Project. Clinical Oncology , 33 (1) e50-e53. 10.1016/j.clon.2020.05.021. Green open access
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Biasco, L; Izotova, N; Rivat, C; Ghorashian, S; Richardson, R; Guvenel, A; Hough, R; ... Amrolia, PJ; + view all (2021) Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients. Nature Cancer , 2 pp. 629-64. 10.1038/s43018-021-00207-7. Green open access
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Bichet, DG; Torra, R; Wallace, E; Hughes, D; Giugliani, R; Skuban, N; Krusinska, E; ... Nicholls, K; + view all (2021) Long-term follow-up of renal function in patients treated with migalastat for Fabry disease. Molecular Genetics and Metabolism Reports , 28 , Article 100786. 10.1016/j.ymgmr.2021.100786. Green open access
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Black, JRM; McGranahan, N; (2021) Genetic and non-genetic clonal diversity in cancer evolution. Nature Reviews Cancer , 21 (6) pp. 379-392. 10.1038/s41568-021-00336-2. Green open access
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Bofinger, R; Weitsman, G; Evans, R; Glaser, M; Sander, K; Allan, H; Hochhauser, D; ... Tabor, AB; + view all (2021) Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors. Nanoscale 10.1039/d1nr02770k. (In press). Green open access
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Bollen, Y; Stelloo, E; van Leenen, P; van den Bos, M; Ponsioen, B; Lu, B; van Roosmalen, MJ; ... Snippert, HJG; + view all (2021) Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nature Genetics 10.1038/s41588-021-00891-2. (In press). Green open access
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Booth, S; Curley, HM; Varnai, C; Arnold, R; Lee, LYW; Campton, NA; Cook, G; ... Palles, C; + view all (2021) Key findings from the UKCCMP cohort of 877 patients with haematological malignancy and COVID-19: disease control as an important factor relative to recent chemotherapy or anti-CD20 therapy. British Journal of Haematology 10.1111/bjh.17937. (In press). Green open access
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Bortolomeazzi, M; Keddar, MR; Montorsi, L; Acha-Sagredo, A; Benedetti, L; Temelkovski, D; Choi, S; ... Ciccarelli, FD; + view all (2021) Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts. Gastroenterology 10.1053/j.gastro.2021.06.064. (In press). Green open access
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Boyle, Eileen M; Deshpande, Shayu; Tytarenko, Ruslana; Ashby, Cody; Wang, Yan; Bauer, Michael A; Johnson, Sarah K; ... Walker, Brian A; + view all (2021) The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma. Nature Communications , 12 , Article 293. 10.1038/s41467-020-20524-2. Green open access
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Breeze, CE; Batorsky, A; Lee, MK; Szeto, MD; Xu, X; McCartney, DL; Jiang, R; ... Franceschini, N; + view all (2021) Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Medicine , 13 (1) , Article 74. 10.1186/s13073-021-00877-z. Green open access
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Brooks, LJ; Clements, MP; Burden, JJ; Kocher, D; Richards, L; Devesa, SC; Zakka, L; ... Parrinello, S; + view all (2021) The white matter is a pro-differentiative niche for glioblastoma. Nature Communications , 12 , Article 2184. 10.1038/s41467-021-22225-w. Green open access
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Buck, M; Poirier, E; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... The Crick COVID-19 Consortium; + view all (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 1 approved with reservations]. Wellcome Open Research , 6 (9) 10.12688/wellcomeopenres.16517.1. Green open access
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Buck, MD; Poirier, EZ; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... Crick COVID-19 Consortium; + view all (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay. Wellcome Open Research , 6 , Article 9. 10.12688/wellcomeopenres.16517.2. Green open access
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Busacca, S; Zhang, Q; Sharkey, A; Dawson, AG; Moore, DA; Waller, DA; Nakas, A; ... Fennell, DA; + view all (2021) Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression. Scientific Reports , 11 (1) , Article 7434. 10.1038/s41598-021-86834-7. Green open access
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Byers, LA; Navarro, A; Schaefer, E; Johnson, M; Özgüroğlu, M; Han, J-Y; Bondarenko, I; ... Forster, M; + view all (2021) A Phase II Trial of Prexasertib (LY2606368) in Patients With Extensive-Stage Small-Cell Lung Cancer. Clinical Lung Cancer , 22 (6) pp. 531-540. 10.1016/j.cllc.2021.04.005. Green open access
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Cabrera, R; Singal, AG; Colombo, M; Kelley, RK; Lee, H; Mospan, AR; Meyer, T; ... Di Bisceglie, AM; + view all (2021) A Real-World Observational Cohort of Patients with Hepatocellular Carcinoma: Design and Rationale for TARGET-HCC. Hepatology Communications , 5 (3) pp. 538-547. 10.1002/hep4.1652. Green open access
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Cai, H; Chew, SK; Li, C; Tsai, MK; Andrejka, L; Murray, CW; Hughes, NW; ... Winslow, MM; + view all (2021) A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer. Cancer Discovery , 11 (7) pp. 1754-1773. 10.1158/2159-8290.CD-20-1325. Green open access
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Camacho-Bydume, C; Wang, T; Sees, JA; Fernandez-Vina, M; Abid, MB; Askar, M; Beitinjaneh, A; ... Hsu, KC; + view all (2021) Specific Class I HLA Supertypes but Not HLA Zygosity or Expression Are Associated with Outcomes following HLA-Matched Allogeneic Hematopoietic Cell Transplant: HLA Supertypes Impact Allogeneic HCT Outcomes. Specific Class I HLA Supertypes but Not HLA Zygosity or Expression Are Associated with Outcomes following HLA-Matched Allogeneic Hematopoietic Cell Transplant: HLA Supertypes Impact Allogeneic HCT Outcomes , 27 (2) 142.e1-142.e11. 10.1016/j.bbmt.2020.10.010. Green open access
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Camilleri, M; Sive, J; Wilson, W; Pang, G; Jenner, R; Phillips, E; Popat, R; ... Yong, K; + view all (2021) COVID-19 and myeloma clinical research - experience from the CARDAMON clinical trial. British Journal of Haematology , 192 (1) E14-E16. 10.1111/bjh.17168. Green open access
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Camilleri, M; Cuadrado, M; Phillips, E; Wilson, W; Jenner, R; Pang, G; Kamora, S; ... Yong, K; + view all (2021) Thrombotic microangiopathy in untreated myeloma patients receiving carfilzomib, cyclophosphamide and dexamethasone on the CARDAMON study. British Journal of Haematology 10.1111/bjh.17377. (In press). Green open access
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Carbó, JM; León, TE; Font-Díaz, J; De la Rosa, JV; Castrillo, A; Picard, FR; Staudenraus, D; ... Valledor, AF; + view all (2021) Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment. Cancer Research , 81 (4) pp. 968-985. 10.1158/0008-5472.CAN-19-3360. Green open access
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Carter, TJ; Agliardi, G; Lin, F-Y; Ellis, M; Jones, C; Robson, M; Richard-Londt, A; ... Chester, K; + view all (2021) Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation. Small , Article e2005241. 10.1002/smll.202005241. (In press). Green open access
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Chambers, P; Wei, L; Forster, MD; Kipps, E; Wong, ICK; Jani, Y; (2021) Evidence to guide the optimal timing for pre-chemotherapy blood tests for early breast, colorectal cancer and diffuse large B-cell lymphoma. Cancer Medicine 10.1002/cam4.4316. (In press). Green open access
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Chan, E; Sammaraiee, Y; Banerjee, G; Martin, AF; Farmer, S; Cowley, P; Sayal, P; ... Werring, DJ; + view all (2021) Neuropsychological and neuroimaging characteristics of classical superficial siderosis. Journal of Neurology , 268 pp. 4238-4247. 10.1007/s00415-021-10548-z. Green open access
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Chen, M; Chen, R; Jin, Y; Li, J; Hu, X; Zhang, J; Fujimoto, J; ... Zhang, J; + view all (2021) Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer. Nature Communications , 12 , Article 6655. 10.1038/s41467-021-26821-8. Green open access
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Chen, X; Zhabyeyev, P; Azad, AK; Vanhaesebroeck, B; Grueter, CE; Murray, AG; Kassiri, Z; (2021) Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction. Journal of Molecular and Cellular Cardiology , 157 pp. 17-30. 10.1016/j.yjmcc.2021.04.004. Green open access
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Chen, S-H; Miles, K; Taylor, SA; Ganeshan, B; Rodriquez, M; Fraioli, F; Wan, S; ... Groves, A; + view all (2021) FDG-PET/CT in colorectal cancer: potential for vascular-metabolic imaging to provide markers of prognosis. European Journal of Nuclear Medicine and Molecular Imaging 10.1007/s00259-021-05318-y. (In press). Green open access
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Childs, A; Zakeri, N; Ma, YT; O’Rourke, J; Ross, P; Hashem, E; Hubner, RA; ... Meyer, T; + view all (2021) Biopsy for advanced hepatocellular carcinoma: results of a multicentre UK audit. British Journal of Cancer 10.1038/s41416-021-01535-2. (In press). Green open access
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Childs, A; Steele, CD; Vesely, C; Rizzo, FMM; Ensell, L; Lowe, H; Dhami, P; ... Meyer, T; + view all (2021) Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms. Endocrine-Related Cancer 10.1530/ERC-21-0179. (In press). Green open access
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Chowdary, Pratima; Shapiro, Susan; Makris, Mike; Evans, Gillian; Boyce, Sara; Talks, Kate; Dolan, Gerry; ... Nathwani, Amit; + view all (2021) Factor IX Expression within the Normal Range Prevents Spontaneous Bleeds Requiring Treatment Following FLT180a Gene Therapy in Patients with Severe Hemophilia B: Long-Term Follow- up Study of the B-Amaze Program. Blood , 138 (Supp 1) , Article 3967. 10.1182/blood-2021-146546. Green open access
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Chung, C-Y; Singh, K; Kotiadis, VN; Valdebenito, GE; Ahn, JH; Topley, E; Tan, J; ... Duchen, MR; + view all (2021) Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation. Nature Communications , 12 (1) , Article 6409. 10.1038/s41467-021-26746-2. Green open access
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Clamp, AR; Lorusso, D; Oza, AM; Aghajanian, C; Oaknin, A; Dean, A; Colombo, N; ... Ledermann, JA; + view all (2021) Rucaparib maintenance treatment for recurrent ovarian carcinoma: the effects of progression-free interval and prior therapies on efficacy and safety in the randomized phase III trial ARIEL3. International Journal of Gynecological Cancer 10.1136/ijgc-2020-002240. (In press). Green open access
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Clark, JJ; Dwyer, D; Pinwill, N; Clark, P; Johnson, P; Hackshaw, A; (2021) The effect of clinical decision making for initiation of systemic anticancer treatments in response to the COVID-19 pandemic in England: a retrospective analysis. The Lancet Oncology , 22 (1) pp. 66-73. 10.1016/S1470-2045(20)30619-7. Green open access
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Cleary, M; Davison, J; Gould, R; Geberhiwot, T; Hughes, D; Mercer, J; Morrison, A; ... Stepien, KM; + view all (2021) Impact of long-term elosulfase alfa treatment on clinical and patient-reported outcomes in patients with mucopolysaccharidosis type IVA: results from a Managed Access Agreement in England. Orphanet Journal of Rare Diseases , 16 , Article 38. 10.1186/s13023-021-01675-x. Green open access
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Coats, T; Bean, D; Basset, A; Sirkis, T; Brammeld, J; Johnson, S; Thomas, I; ... Dillon, R; + view all (2021) A novel algorithmic approach to generate consensus treatment guidelines in adult acute myeloid leukaemia. British Journal of Haematology 10.1111/bjh.18013. (In press). Green open access
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Stavropoulou, A; Szmul, A; Chandy, E; Veiga, C; Landau, D; McClelland, JR; (2021) A multichannel feature-based approach for longitudinal lung CT registration in the presence of radiation induced lung damage. Physics in Medicine & Biology 10.1088/1361-6560/ac1b1d. (In press). Green open access
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Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; ... Bauer, DLV; + view all (2021) Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. The Lancet 10.1016/s0140-6736(21)01290-3. (In press). Green open access
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Waterland, JL; McCourt, O; Edbrooke, L; Granger, CL; Ismail, H; Riedel, B; Denehy, L; (2021) Efficacy of Prehabilitation Including Exercise on Postoperative Outcomes Following Abdominal Cancer Surgery: A Systematic Review and Meta-Analysis. Frontiers in Surgery , 8 , Article 628848. 10.3389/fsurg.2021.628848. Green open access
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Watt, S; Vasquez, L; Walter, K; Mann, AL; Kundu, K; Chen, L; Sims, Y; ... Soranzo, N; + view all (2021) Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease. Nature Communications , 12 , Article 2298. 10.1038/s41467-021-22548-8. Green open access
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Wong, YNS; Sng, CCT; Ottaviani, D; Patel, G; Chowdhury, A; Earnshaw, I; Sinclair, A; ... Lee, AJX; + view all (2021) Systemic anti-cancer therapy and metastatic cancer are independent mortality risk factors during two uk waves of the covid-19 pandemic at university college london hospital. Cancers , 13 (23) , Article 6085. 10.3390/cancers13236085. Green open access
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Wu, F; Watanabe, N; Tzioni, M-M; Akarca, A; Zhang, C; Li, Y; Chen, Z; ... Du, M-Q; + view all (2021) Thyroid MALT lymphoma: self-harm to gain potential T-cell help. Leukemia 10.1038/s41375-021-01289-z. Green open access
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Wu, Y; Biswas, D; Swanton, C; (2021) Impact of cancer evolution on immune surveillance and checkpoint inhibitor response. Seminars in Cancer Biology 10.1016/j.semcancer.2021.02.013. (In press). Green open access
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Yeo, GHT; Juez, O; Chen, Q; Banerjee, B; Chu, L; Shen, MW; Sabry, M; ... Gifford, DK; + view all (2021) Detection of gene cis-regulatory element perturbations in single-cell transcriptomes. PLoS Computational Biology , 17 (3) , Article e1008789. 10.1371/journal.pcbi.1008789. (In press). Green open access
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Yong, KL; Hinsley, S; Auner, HW; Bygrave, C; Kaiser, MF; Ramasamy, K; De Tute, RM; ... Brown, SR; + view all (2021) Carfilzomib or bortezomib in combination with cyclophosphamide and dexamethasone followed by carfilzomib maintenance for patients with multiple myeloma after one prior therapy: results from a multi-centre, phase II, randomized, controlled trial (MUKfive). Haematologica 10.3324/haematol.2021.278399. (In press). Green open access
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Zhang, M; Luo, J-L; Sun, Q; Harber, J; Dawson, AG; Nakas, A; Busacca, S; ... Fennell, DA; + view all (2021) Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature Communications , 12 (1) , Article 1751. 10.1038/s41467-021-21798-w. Green open access
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Zhao, T; Siu, I-M; Williamson, T; Zhang, H; Ji, C; Burger, PC; Connis, N; ... Gallia, GL; + view all (2021) AZD8055 enhances in vivo efficacy of afatinib in chordomas. The Journal of Pathology , 255 (1) pp. 72-83. 10.1002/path.5739. Green open access
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Zhao, Y; Morka, N; Simpson, BSS; Freeman, A; Kirkham, A; Kelly, D; Whitaker, HC; ... Norris, JM; + view all (2021) Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis. BMJ Open , 11 (12) , Article e052277. 10.1136/bmjopen-2021-052277. Green open access
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Zhou, X; Liang, T; Deng, J; Ng, K; Li, M; Lv, C; Chen, J; ... Wang, P; + view all (2021) Differential and Prognostic Significance of HOXB7 in Gliomas. Frontiers in Cell and Developmental Biology , 9 , Article 697086. 10.3389/fcell.2021.697086. Green open access
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Zhu, AX; Macarulla, T; Javle, MM; Kelley, RK; Lubner, SJ; Adeva, J; Cleary, JM; ... Abou-Alfa, GK; + view all (2021) Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial. JAMA Oncology 10.1001/jamaoncol.2021.3836. (In press). Green open access
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Ziff, Monica; Lawson, Gabrielle; De-Silva, Dunnya; Cheesman, Simon; Kyriakou, Charalampia; Mahmood, Shameem; Papanikolaou, Xenofon; ... Popat, Rakesh; + view all (2021) Ixazomib with lenalidomide and dexamethasone for patients with relapsed multiple myeloma: impact of 17p deletion and sensitivity to proteasome inhibitors from a real world data-set. Leukemia & Lymphoma , 62 (5) pp. 1243-1246. 10.1080/10428194.2020.1864356. Green open access
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Zoumpoulidou, G; Alvarez-Mendoza, C; Mancusi, C; Ahmed, R-M; Denman, M; Steele, CD; Tarabichi, M; ... Mittnacht, S; + view all (2021) Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma. Nature Communications , 12 (1) , Article 7064. 10.1038/s41467-021-27291-8. Green open access
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Proceedings paper

Barmpoutis, P; Kayhanian, H; Waddingham, W; Alexander, DC; Jansen, M; (2021) Three-dimensional tumour microenvironment reconstruction and tumour-immune interactions' analysis. In: 2021 Digital Image Computing: Techniques and Applications (DICTA). IEEE: Gold Coast, Australia. Green open access
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Hagos, YB; Lecat, CSY; Patel, D; Lee, L; Tran, TA; Justo, MR; Yong, K; (2021) Cell abundance aware deep learning for cell detection on highly imbalanced pathological data. In: 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI). (pp. pp. 1438-1442). IEEE: Nice, France. Green open access
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Sashittal, P; Zaccaria, S; El-Kebir, M; (2021) Parsimonious clone tree reconciliation in cancer. In: 21st International Workshop on Algorithms in Bioinformatics (WABI 2021). (pp. 9:1-9:21). Schloss Dagstuhl -- Leibniz-Zentrum für Informatik: Dagstuhl, Germany. Green open access
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Zhang, Hanyun; Grunewald, Tami; Akarca, Ayse U; Ledermann, Jonathan A; Marafioti, Teresa; Yuan, Yinyin; (2021) Symmetric Dense Inception Network for Simultaneous Cell Detection and Classification in Multiplex Immunohistochemistry Images. In: Atzori, Manfredo and Burlutskiy, Nikolay and Ciompi, Francesco and Li, Zhang and Minhas, Fayyaz and Müller, Henning and Peng, Tingying and Rajpoot, Nasir and Torben­_Nielsen, Ben and van der Laak, Jeroen and Veta, Mitko and Yuan, Yinyin and Zlobec, Inti, (eds.) Proceedings of the MICCAI Workshop on Computational Pathology. (pp. pp. 246-257). PMLR Green open access
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Report

Gomez, Charles; (2021) Atrial fibrillation: diagnosis and management. (NICE guideline NG196 ). National Institute for Health and Care Excellence (NICE) Green open access
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Working / discussion paper

Fendler, Annika; Au, Lewis; Shepherd, Scott TC; Byrne, Fiona; Cerrone, Maddalena; Boos, Laura Amanda; Rzeniewicz, Karolina; ... Turajlic, Samra; + view all (2021) Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Research Square: Durham, NC, USA. Green open access
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Garcia-Diaz, Claudia; Mereu, Elisabetta; Clements, Melanie; Pöysti, Anni; Galvez-Cancino, Felipe; Castillo, Simon; Courtot, Lilas; ... Parrinello, Simona; + view all (2021) Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin. bioRxiv: Cold Spring Harbor, NY, USA. Green open access
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Poster

Stavropoulou, K-A; Szmul, A; Chandy, E; Veiga, C; Landau, D; McClelland, J; (2021) A Multichannel Feature-Based Approach for Longitudinal Lung CT Registration in the Presence of Radiation Induced Lung Damage. Presented at: AAPM 63rd Annual Meeting and Exhibition (AAPM 2021), Virtual conference. Green open access
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Thesis

Abbosh, Christopher; (2021) Cell-free DNA in early-stage non-small cell lung cancer. Doctoral thesis (Ph.D), UCL (University College London).

Beaton, Laura Elizabeth; (2021) Vandetanib-eluting radiopaque beads and stereotactic body radiotherapy in the treatment of liver cancers. Doctoral thesis (M.D(Res)), UCL (University College London). Green open access
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Biswas, Dhruva; (2021) Molecular Portraits of Cancer Evolution and Ecology. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Brimble, Mark; (2021) Characterisation Of Adeno-Associated Virus DNA contaminants and Development of a P5 promoter replacement, high purity Adeno-Associated Virus production system. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Chalk, Avigayil; (2021) Combining ATR inhibition with topoisomerase I inhibitors for the treatment of colorectal cancer. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Dale, Katie; (2021) Functional identification and investigation of genes initiating chromosomal instability using CRISPR activation and high-throughput automated image analysis. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Farah, Nadine Hani Rashad; (2021) Identifying novel therapeutic targets and prognostic markers through analysis of allele specific alterations in T-cell acute lymphoblastic leukaemia. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Gao, Fangfei; (2021) HER family receptor activation and dimerisation in colorectal cancer and cancer-derived exosomes. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Jayaram, Anuradha Krishna; (2021) Leveraging circulating tumour DNA to dissect the evolutionary genomic dynamics of drug resistance in prostate cancer. Doctoral thesis (Ph.D), UCL (University College London).

Kayhanian, Hamzeh; (2021) Role of secondary mismatch repair (MMR) frameshifts in the evolution of microsatellite instable (MSI) colorectal cancer. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Lau, Evelyn Keet Wai; (2021) Genomic and epigenomic impact of oncogenic mutation in the PIK3CA gene. Doctoral thesis (Ph.D), UCL (University College London).

Le Grange, Franel; (2021) Advanced radiotherapy techniques: Improving outcomes in sarcoma. Doctoral thesis (M.D(Res)), UCL (University College London). Green open access
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Mancusi, Caterina; (2021) Identification of novel therapeutic approaches for the treatment of tumours characterised by mutations in the Retinoblastoma tumour suppressor gene (RB1). Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Mitchell, Rachel; (2021) IKZF1 lesions in adult acute lymphoblastic leukaemia - the chicken or the egg? Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Moghul, Muhammad Ismail; (2021) Imputation Aided Methylation Analysis. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Nannini, Francesco; (2021) Development of novel anti-mouse CD19 single-chain variable-fragments and establishment of an immunocompetent B-cell malignancy mouse model for the investigation of CAR-T cell therapies. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Pearce, David; (2021) Investigation of fibulin-2 in pulmonary fibrosis. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Porter, Hayley; (2021) Identification of diverse cohesin-independent SA interactors that inform SA-specific functions. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Righi, Matteo; (2021) Enhancement of Adoptive Cell Therapies via novel engineered Chimeric Cytokine Receptor. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Robert De Massy, Marc Louis; (2021) Features of the intratumoral T cell receptor repertoire associated with antigen exposure in cancer patients. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Ros Soto, Jose; (2021) Vitamin D and Immune Responses in Haematopoietic Stem Cell Transplantation. Doctoral thesis (M.D(Res)), UCL (University College London). Green open access
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Sari, Sibel; (2021) Phenotypic characterization of SHOC2 inactivation in adult mice. Doctoral thesis (Ph.D), UCL (University College London).

Stubbs, Matthew James; (2021) Characterisation of Immune Thrombotic Thrombocytopenic Purpura utilising deep phenotyping and genotyping via genome wide association study. Doctoral thesis (Ph.D), UCL (University College London).

Vila De Mucha, Maria Antonieta; (2021) Transcriptional regulation of tumour infiltrating cytotoxic CD4+ T cell differentiation. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Wong, Yien Ning Sophia; (2021) Identification of urine derived lymphocytes as a non-invasive measure of the tumour immune microenvironment in bladder cancer. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Yim, Richard Hwarn Yip; (2021) Leveraging of single molecule sequencing methods for less invasive cancer detection. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Sun Oct 20 23:40:56 2024 BST.